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2010 | OriginalPaper | Chapter
Design and Characterization of a Signal Conditioning Microchip and Thin-Film Microelectrode Array for High Spatial Resolution Cardiac Mapping
Authors : Huihang Dong, Douglas Jackson, Thomas Roussel, Derek Dosdal, Raymond Ideker, John Naber, Steven Koenig, Robert Keynton
Published in: 6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore
Publisher: Springer Berlin Heidelberg
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A Thin-Film Microelectrode Array (TFMEA) capable of recording electrical activities of the heart with high spatial resolution, on the order of individual myocytes, was developed and characterized to study the mechanisms of arrhythmias. A customized multichannel signal conditioning microchip (SCM) consisting of a pre-amplification stage and band-pass filter was interfaced directly to the electrodes on the TFMEA to improve the signal-to-noise ratios (SNRs). The results suggest that the TFMEA-SCM system will greatly enhance the spatial resolution and improve signal quality for high resolution cardiac mapping.