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01-09-2020 | NANOMATERIALS IN BIOLOGY AND MEDICINE

Detection of Cells Containing Internalized Multidomain Magnetic Iron (II, III) Oxide Nanoparticles Using the Magnetic Resonance Imaging Method

Authors: N. I. Enukashvily, I. E. Kotkas, D. S. Bogolyubov, A. V. Kotova, I. O. Bogolyubova, V. V. Bagaeva, K. A. Levchuk, I. I. Maslennikova, D. A. Ivolgin, A. Yu. Artamonov, N. V. Marchenko, I. V. Mindukshev

Published in: Technical Physics | Issue 9/2020

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Abstract

This study evaluated the feasibility of using uncoated iron (II, III) oxide nanoparticles (IONP) obtained by electric explosion of wire in air for labelling living mesenchymal stromal cells and their subsequent visualization by magnetic resonance imaging (MRI) using the 1T and 1.5T clinical MRI scanners. The uptake of uncoated IONP by MSC was demonstrated for the wide range of IONP concentration in the cell culture medium. The cells did not change their proliferative activity, viability, and the set of surface markers. Iron oxide nanoparticles obtained by an electric explosion of wire in an atmosphere of air had a shape close to spherical. According to dynamic lateral light scattering, laser diffraction, and transmission electron microscopy, the particle size varied from 14 to 136 nm. Particles up to 136 nm accounted for 75%, while particles less than 36 nm accounted for 10%. A wide range of particle sizes made it possible to select MRI parameters suitable for labelled cells detection in animal tissues in both the T2 and the T1 relaxation mode.

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C. Villa, S. Erratico, P. Razini, F. Fiori, F. Rustichelli, Y. Torrente, and M. Belicchi, Int. J. Mol. Sci. 11 (3), 1070 (2010). https://doi.org/10.3390/ijms11031070CrossRef

D. J. Korchinski, M. Taha, R. Yang, N. Nathoo, and J. F. Dunn, Magn. Reson. Insights, No. 8, 15 (2015). https://doi.org/10.4137/MRI.S23557

Ch. Kittel, Introduction to Solid State Physics (Wiley, New York, 1953).MATH

A. I. Zhernovoy, Nauch. Priborostroen. 28 (2), 45 (2018).CrossRef

A. G. Kolhatkar, A. C. Jamison, D. Litvinov, R. C. Willson, and T. R. Lee, Int. J. Mol. Sci. 14 (8), 15977 (2013). https://doi.org/10.3390/ijms140815977CrossRef

N. M. Yudintceva, Y. A. Nashchekina, M. I. Blinova, L. V. Smagina, M. A. Shevtsov, and I. V. Voronkina, FEBS J. 284 (S1), 382 (2017). https://doi.org/10.1111/febs.14174CrossRef

Wahajuddin and S. Arora, Int. J. Nanomed. 7, 3445 (2012). https://doi.org/10.2147/IJN.S30320CrossRef

H. Elkhenany, M. Abd Elkodous, N. I. Ghoneim, T. A. Ahmed, S. M. Ahmed, I. K. Mohamed, and N. El-Badri, Int. J. Biol. Macromol. 143, 763 (2019). https://doi.org/10.1016/j.ijbiomac.2019.10.031CrossRef

L. S. Arias, J. P. Pessan, A. P. M. Vieira, T. M. Toito de Lima, A. C. B. Delbem, and D. R. Monteiro, Antibiotics (Basel, Switz.) 7 (2), 46 (2018). https://doi.org/10.3390/antibiotics7020046

10.

A. Jordan, P. Wust, R. Scholz, B. Tesche, H. Fähling, T. Mitrovics, T. Vogl, J. Cervós-navarro, and R. Felix, Int. J. Hyperthermia 12 (6), 705 (1996). https://doi.org/10.3109/02656739609027678CrossRef

11.

Q. Feng, Y. Liu, J. Huang, K. Chen, J. Huang, and K. Xiao, Sci. Rep. 8 (1), 2082 (2018). https://doi.org/10.1038/s41598-018-19628-zADSCrossRef

12.

M. I. Lerner, Doctoral Dissertation in Engineering (Tomsk Polytech. Univ., Tomsk, 2007).

13.

M. I. Lerner, N. V. Svarovskaya, S. G. Psakhie, and O. V. Bakina, Nanotechnol. Russ. 4 (11–12), 741 (2009). https://doi.org/10.1134/S1995078009110019CrossRef

14.

DelsaMax PRO Light Scattering Analyzer. Instructions for Use (Beckman Coulter, 2013), p. 188.

15.

I. Mindukshev, S. Gambaryan, L. Kehrer, C. Schuetz, A. Kobsar, N. Rukoyatkina, V. O. Nikolaev, A. Krivchenko, S. P. Watson, U. Walter, and J. Geiger, Clin. Chem. Lab. Med. 50 (7), 1253 (2012).CrossRef

16.

A. A. Aisenstadt, N. I. Enukashvili, T. L. Zolina, L. V. Alexandrova, and A. B. Smoljaninov, Mechnikov Vestn. Severo-Zapad. Gos. Med. Inst. 7 (2), 14 (2015).

17.

V. V. Bagaeva, A. A. Aizenshtadt, L. V. Aleksandrova, et. al. RF Patent No. 2620981 C2, Byull. Izobret., No. 16, 1 (2017).

18.

M. Dominici, K. Le Blanc, I. Mueller, I. Slaper-Cortenbach, F. Marini, D. Krause, R. Deans, A. Keating, D. J. Prockop, and E. Horwitz, Cytotherapy 8 (4), 315 (2006). https://doi.org/10.1080/14653240600855905CrossRef

19.

L. Li, K. Y. Mak, J. Shi, H. K. Koon, C. H. Leung, C. M. Wong, C. W. Leung, C. S. Mak, N. M. Chan, W. Zhong, K. W. Lin, E. X. Wu, and P. W. Pong, J. Nanosci. Nanotechnol. 12 (12), 9010 (2012). https://doi.org/10.1166/jnn.2012.6755CrossRef

20.

R. Das, B. K. Das, R. Shukla, and A. Shyam, J. Phys.: Conf. Ser. 390 (1), 2051 (2012). https://doi.org/10.1088/1742-6596/390/1/012051CrossRef

21.

Q. Li, C. W. Kartikowati, S. Horie, T. Ogi, T. Iwaki, and K. Okuyama, Sci. Rep. 7 (1), 9894 (2017). https://doi.org/10.1038/s41598-017-09897-5ADSCrossRef

22.

N. V. Abramov and P. P. Gorbik, Poverkhnost, No. 4(19), 246 (2012).

23.

U. Jeong, X. Teng, Y. Wang, H. Yang, and Y. Xia, Adv. Mater. 19 (1), 33 (2007). https://doi.org/10.1002/adma.200600674CrossRef

Title: Detection of Cells Containing Internalized Multidomain Magnetic Iron (II, III) Oxide Nanoparticles Using the Magnetic Resonance Imaging Method
Authors: N. I. Enukashvily
I. E. Kotkas
D. S. Bogolyubov
A. V. Kotova
I. O. Bogolyubova
V. V. Bagaeva
K. A. Levchuk
I. I. Maslennikova
D. A. Ivolgin
A. Yu. Artamonov
N. V. Marchenko
I. V. Mindukshev
Publication date: 01-09-2020
Publisher: Pleiades Publishing
Published in: Technical Physics / Issue 9/2020
Print ISSN: 1063-7842
Electronic ISSN: 1090-6525
DOI: https://doi.org/10.1134/S1063784220090145

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