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2020 | OriginalPaper | Chapter

Effects of Green Silver Nanoparticles on CCl4 Injured Albino Rats’ Liver

Authors : Sh. Kazaryan, M. Petrosyan, L. Rshtuni, V. Dabaghyan, A. Hovhannisyan

Published in: 4th International Conference on Nanotechnologies and Biomedical Engineering

Publisher: Springer International Publishing

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Abstract

Nanoparticles green synthesis by plants and extracts is very cost-effective and can be used as an economic and environment friendly alternative in large-scale production. But the effect of these structures on the liver isn’t fully investigated. In this study green silver nanoparticles (AgNPs) were synthesized by O. araratum 50% ethanol extract that has the highest antiradical activity. It was found that treatment by O. araratum extract leads to rats’ liver structure normalization and normalization of liver injury markers’ activity. Meanwhile, AgNPs at 20 mg/kg body weight dose leads to fibroblasts activation and fibrosis.

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Metadata
Title
Effects of Green Silver Nanoparticles on CCl4 Injured Albino Rats’ Liver
Authors
Sh. Kazaryan
M. Petrosyan
L. Rshtuni
V. Dabaghyan
A. Hovhannisyan
Copyright Year
2020
DOI
https://doi.org/10.1007/978-3-030-31866-6_27