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Published in:
2020 | OriginalPaper | Chapter
Evaluation of Left Ventricular Ejection Fraction Obtained from 201Tl Myocardial Perfusion Scan by CZT Cardiac Camera
Authors : Hsiao-Ling Chiang, Chien-Hsin Ting, Cheng-Pe Chang, Bang-Hung Yang, Jyh-Shyan Leu, Chi-Long Juang, Wen-Sheng Huang
Published in: Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices
Publisher: Springer International Publishing
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Abstract
Taking advantage of high energy and spatial resolution and high count sensitivity, the ultrafast cardiac γ-camera with cadmium-zinc-telluride (CZT)-based detectors has become popular in practice for myocardial perfusion imaging (MPI). The shorter imaging time with better imaging quality using CZT detectors compared to conventional ones makes it feasible to perform the left ventricular ejection fraction (LVEF) in the meantime of doing 201Tl MPI. The aim of this study was to compare LVEF from 201Tl MPI using a CZT with that from first-pass radionuclide angiography (FPRA) using a NaI camera.
A total of 117 patients (aged 81 ± 13 years old) were collected. All underwent 201Tl MPI using a CZT camera (Discovery NM530c) and FPRA using a conventional camera (Symbia E Signal Head System) in 2 wks. Correlations of LVEF obtained from these two examinations were evaluated by SPSS 20.0 statistical software.
Our results showed that the mean LVEF measured from MPI and FPRA were 54 ± 18% and 51 ± 16%, respectively. A good linear correlation was found between both methods (r: 0.861, p < 0.0001). It also showed a good agreement and LVEF prediction rates (k = 0.83) obtained from these two measurements. Tl-201 MPI with CZT camera is thus capable to offer a reliable clinical LVEF references.