2007 | OriginalPaper | Chapter
Groupwise Combined Segmentation and Registration for Atlas Construction
Authors : Kanwal K. Bhatia, Paul Aljabar, James P. Boardman, Latha Srinivasan, Maria Murgasova, Serena J. Counsell, Mary A. Rutherford, Joseph V. Hajnal, A. David Edwards, Daniel Rueckert
Published in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007
Publisher: Springer Berlin Heidelberg
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The creation of average anatomical atlases has been a growing area of research in recent years. It is of increased value to construct representations of, not only intensity atlases, but also their segmentation into required tissues or structures. This paper presents novel
groupwise combined segmentation and registration
approaches, which aim to simultaneously improve both the alignment of intensity images to their average shape, as well as the segmentations of structures in the average space. An iterative EM framework is used to build average 3D MR atlases of populations for which prior atlases do not currently exist: preterm infants at one- and two-years old. These have been used to quantify the growth of tissues occurring between these ages.