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Published in:
2012 | OriginalPaper | Chapter
Imaging with Optimized Magnetite MPI Tracers
Authors : R. Matthew Ferguson, Amit P. Khandhar, Patrick W. Goodwill, Steven M. Conolly, Kannan M. Krishnan
Published in: Magnetic Particle Imaging
Publisher: Springer Berlin Heidelberg
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Magnetite nanoparticle (MNP) tracers can be optimized for Magnetic Particle Imaging (MPI) by tuning their magnetic core size and size distribution. In previous work, our group showed that ~15 nm MNPs were optimal at 250 khz by synthesizing a series of tracers with tuned size and narrow size distributions. This optimization approach is general, and here we present experimental results that demonstrate that the same principles apply at 25 khz excitation. The key result of this work is that MPI spatial resolution can be improved by the appropriate selection of MNPs.