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Published in:
2019 | OriginalPaper | Chapter
Inference of an Extended Short Fiber Bundle Atlas Using Sulcus-Based Constraints for a Diffeomorphic Inter-subject Alignment
Authors : Nicole Labra Avila, Jessica Lebenberg, Denis Rivière, Guillaume Auzias, Clara Fischer, Fabrice Poupon, Pamela Guevara, Cyril Poupon, Jean-François Mangin
Published in: Computational Diffusion MRI
Publisher: Springer International Publishing
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Abstract
We present a new framework for the creation of an extended atlas of short fiber bundles between 20 and 80 mm length. This method uses a Diffeomorphic inter-subject alignment procedure including information of cortical foldings and forces the accurate match of the sulci that have to be circumvented by the U-bundles. Then, a clustering is performed to extract the most reproducible bundles across subjects. First results show an increased number of U-bundles consistently mapped in the general population compared with previous atlases created from the same database. Future analysis over this new extended Brain atlas may improve our understanding of the relationship between the folding pattern and the U-bundle variability. The ultimate aim will be the possibility to detect abnormal configurations induced by developmental issues.