Skip to main content
Disciplines
Automotive Business IT + Informatics Construction + Real Estate Electrical Engineering + Electronics Energy + Sustainability Insurance + Risk Finance + Banking Management + Leadership Marketing + Sales Mechanical Engineering + Materials
Events
DE
EN
Books
Journals
Topic Page
Marketing
Start single access now
Access for companies
EXTENDED SEARCH
Log in
Top
Published in:
Identification of Coding Regions in Prokaryotic DNA Sequences Using Bayesian Classification Read chapter Read first chapter

2020 | OriginalPaper | Chapter

Influence of Sarcopenia on Bone Health Parameters in a Group of Elderly Lebanese Men

Authors : Amal Antoun, Hayman Saddick, Antonio Pinti, Riad Nasr, Eric Watelain, Eric Lespessailles, Hechmi Toumi, Rawad El Hage

Published in: Bioinformatics and Biomedical Engineering

Publisher: Springer International Publishing

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

Sarcopenia is a disease characterized by the loss of muscle mass and strength. The aim of the current study was to explore the influence of sarcopenia on bone health parameters in a group of elderly Lebanese men. To do so, we compared bone health parameters (Bone Mineral Content (BMC), Bone Mineral Density (BMD) and femoral neck geometry indices) in a group of elderly men with sarcopenia and a group of elderly men with normal Skeletal Muscle mass Index (SMI). 23 sarcopenic men (SMI < 7 kg/m2) and 23 men with normal SMI (>7 kg/m2) participated in our study. Body composition and bone variables were measured by Dual-energy X-ray Absorptiometry (DXA). DXA measurements were completed for the Whole Body (WB), Lumbar spine (L1–L4), Total Hip (TH) and Femoral Neck (FN). Hip geometry parameters including Cross-Sectional Area (CSA), Cross-Sectional Moment of Inertia (CSMI), section modulus (Z), Strength Index (SI) and Buckling Ratio (BR) were derived by DXA. Age and height were not significantly different between the two groups. Weight, Body Mass Index (BMI), lean mass, fat mass, appendicular lean mass, SMI, WB BMC, TH BMD, FN BMD, CSA, CSMI and Z were significantly higher in non-sarcopenic men compared to sarcopenic men. In the whole population, lean mass was the strongest determinant of bone health parameters. After adjusting for lean mass, there were no significant differences regarding bone health parameters between the two groups. In conclusion, the present study suggests that sarcopenia negatively influences bone health parameters in elderly Lebanese men.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

inform now
previous chapter Stability of Feature Selection Methods: A Study of Metrics Across Different Gene Expression Datasets
next chapter Novel Thermal Image Classification Based on Techniques Derived from Mathematical Morphology: Case of Breast Cancer
Literature
1.
2.
Friedman, A.W.: Important determinants of bone strength: beyond bone mineral density. J. Clin. Rheumatol. 12(2), 70–77 (2006)PubMedCrossRef
3.
Ammann, P., Rizzoli, R.: Bone strength and its determinants. Osteoporos. Int. 14(Suppl 3), S13–S18 (2003)PubMedCrossRef
4.
5.
Rizzoli, R., Bonjour, J.P., Ferrari, S.L.: Osteoporosis, genetics and hormones. J. Mol. Endocrinol. 26(2), 79–94 (2001)PubMedCrossRef
6.
Beck, B.R., Snow, C.M.: Bone health across the lifespan–exercising our options. Exerc. Sport Sci. Rev. 31(3), 117–122 (2003)PubMedCrossRef
7.
Petit, M.A., Beck, T.J., Kontulainen, S.A.: Examining the developing bone: What do we measure and how do we do it? J. Musculoskelet. Neuronal Interact. 5(3), 213–224 (2005)PubMed
8.
9.
10.
Monge, M.C.: Optimizing bone health in adolescents. Curr. Opin. Obstet. Gynecol. 30(5), 310–315 (2018)PubMed
11.
Bonjour, J.P., Chevalley, T., Rizzoli, R., Ferrari, S.: Gene-environment interactions in the skeletal response to nutrition and exercise during growth. Med. Sport Sci. 51, 64–80 (2007)PubMedCrossRef
12.
Bonjour, J.P., Chevalley, T., Ferrari, S., Rizzoli, R.: The importance and relevance of peak bone mass in the prevalence of osteoporosis. Salud Publica Mex. 51(Suppl 1), S5–S17 (2009)PubMed
13.
Bonjour, J.P., Chevalley, T.: Pubertal timing, bone acquisition, and risk of fracture throughout life. Endocr. Rev. 35(5), 820–847 (2014)PubMedCrossRef
14.
El Hage, R., Jacob, C., Moussa, E., Jaffré, C., Baddoura, R.: Bone mass in a group of Lebanese girls from Beirut and French girls from Orleans. J. Med. Liban. 59(3), 131–135 (2011)PubMed
15.
El Hage, R., Baddoura, R.: Anthropometric predictors of geometric indices of hip bone strength in a group of Lebanese postmenopausal women. J Clin Densitom. 15(2), 191–197 (2012)PubMedCrossRef
16.
El Hage, R., Jacob, C., Moussa, E., Baddoura, R.: Relative importance of lean mass and fat mass on bone mineral density in a group of Lebanese postmenopausal women. J. Clin. Densitom. 14(3), 326–331 (2011)PubMedCrossRef
17.
Ayoub, M.L., et al.: DXA-based variables and osteoporotic fractures in Lebanese postmenopausal women. Orthop. Traumatol. Surg. Res. 100(8), 855–858 (2014)PubMedCrossRef
18.
19.
El Hage, R., et al.: Influence of age, morphological characteristics, and lumbar spine bone mineral density on lumbar spine trabecular bone score in Lebanese women. J. Clin. Densitom. 17(3), 434–435 (2014)PubMedCrossRef
20.
Maalouf, G., et al.: Epidemiology of hip fractures in Lebanon: a nationwide survey. Orthop. Traumatol. Surg. Res. 99(6), 675–680 (2013)PubMedCrossRef
21.
El Hage, R., Mina, F., Ayoub, M.L., Theunynck, D., Baddoura, R.: Relative importance of lean mass and fat mass on bone mineral density in a group of Lebanese elderly men. J. Med. Liban. 60(3), 136–141 (2012)PubMed
22.
El Hage, R., Theunynck, D., Rocher, E., Baddoura, R.: Geometric indices of hip bone strength in overweight and control elderly men. J. Med. Liban. 62(3), 150–155 (2014)PubMed
23.
El-Hajj Fuleihan, G., Baddoura, R., Awada, H., Salam, N., Salamoun, M., Rizk, P.: Low peak bone mineral density in healthy Lebanese subjects. Bone 31(4), 520–528 (2002)PubMedCrossRef
24.
Arabi, A., et al.: Bone mineral density by age, gender, pubertal stages, and socioeconomic status in healthy Lebanese children and adolescents. Bone 35(5), 1169–1179 (2004)PubMedCrossRef
25.
El Hage, R., Jacob, C., Moussa, E., Jaffré, C., Benhamou, C.L.: Daily calcium intake and body mass index in a group of Lebanese adolescents. J. Med. Liban. 57(4), 253–257 (2009)PubMed
26.
Salamoun, M.M., et al.: Low calcium and vitamin D intake in healthy children and adolescents and their correlates. Eur. J. Clin. Nutr. 59(2), 177–184 (2005)PubMedCrossRef
27.
Gannagé-Yared, M.H., Chemali, R., Yaacoub, N., Halaby, G.: Hypovitaminosis D in a sunny country: relation to lifestyle and bone markers. J. Bone Miner. Res. 15(9), 1856–1862 (2000)PubMedCrossRef
28.
Gannagé-Yared, M.H., Chemali, R., Sfeir, C., Maalouf, G., Halaby, G.: Dietary calcium and vitamin D intake in an adult Middle Eastern population: food sources and relation to lifestyle and PTH. Int. J. Vitam. Nutr. Res. 75(4), 281–289 (2005)PubMedCrossRef
29.
Fazah, A., Jacob, C., Moussa, E., El-Hage, R., Youssef, H., Delamarche, P.: Activity, inactivity and quality of life among Lebanese adolescents. Pediatr. Int. 52(4), 573–578 (2010)PubMedCrossRef
30.
Nasreddine, L., et al.: Dietary, lifestyle and socio-economic correlates of overweight, obesity and central adiposity in Lebanese children and adolescents. Nutrients 6(3), 1038–1062 (2014)PubMedPubMedCentralCrossRef
31.
Naja, F., Hwalla, N., Itani, L., Karam, S., Sibai, A.M., Nasreddine, L.: A Western dietary pattern is associated with overweight and obesity in a national sample of Lebanese adolescents (13–19 years): a cross-sectional study. Br. J. Nutr. 114(11), 1909–1919 (2015)PubMedPubMedCentralCrossRef
32.
El Hage, Z., et al.: Bone mineral content and density in obese, overweight and normal weight adolescent boys. J. Med. Liban. 61(3), 148–154 (2013)PubMed
33.
El Hage, R.: Geometric indices of hip bone strength in obese, overweight, and normal-weight adolescent boys. Osteoporos. Int. 23(5), 1593–1600 (2012)PubMedCrossRef
34.
Arabi, A., Baddoura, R., Awada, H., Salamoun, M., Ayoub, G., El-Hajj, F.G.: Hypovitaminosis D osteopathy: is it mediated through PTH, lean mass, or is it a direct effect? Bone 39(2), 268–275 (2006)PubMedCrossRef
35.
Arabi, A., Baddoura, R., El-Rassi, R., El-Hajj, F.G.: Age but not gender modulates the relationship between PTH and vitamin D. Bone 47(2), 408–412 (2010)PubMedCrossRef
36.
Cruz-Jentoft, A.J., et al.: Writing group for the European working group on Sarcopenia in older people 2 (EWGSOP2), and the extended group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 48(4), 601 (2019)PubMedPubMedCentralCrossRef
37.
Beaudart C, et al.: Sarcopenia in daily practice: assessment and management. BMC Geriatr. 16(1):170 (2016)
38.
39.
Hirschfeld, H.P., Kinsella, R., Duque, G.: Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos. Int. 28(10), 2781–2790 (2017)PubMedCrossRef
40.
Khawaja, A., et al.: Does muscular power predict bone mineral density in young adults? J. Clin. Densitom. 22(3), 311–320 (2019)PubMedCrossRef
41.
Berro, A.J., et al.: Physical performance variables and bone parameters in a group of young overweight and obese women. J Clin Densitom. 22(2), 293–299 (2019)PubMedCrossRef
42.
Al Rassy, N., et al.: The relationships between bone variables and physical fitness across the BMI spectrum in young adult women. J. Bone Miner. Metab. 37(3), 520–528 (2019)PubMedCrossRef
43.
44.
El Khoury, G., et al.: Bone Variables in active overweight/obese men and sedentary overweight/obese men. J. Clin. Densitom. 20(2), 239–246 (2017)PubMedCrossRef
45.
El Khoury, C., et al.: Physical performance variables and bone mineral density in a group of young overweight and obese men. J. Clin. Densitom. 21(1), 41–47 (2018)PubMedCrossRef
46.
Zakhem, E., et al.: Performance physique et densité minérale osseuse chez de jeunes adultes libanais. J. Med. Liban. 64(4), 193–199 (2016)PubMed
47.
El Hage, R., et al.: Maximal oxygen consumption and bone mineral density in a group of young Lebanese adults. J. Clin. Densitom. 17(2), 320–324 (2014)PubMedCrossRef
48.
Roberts, H.C., et al.: A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing 40(4), 423–429 (2011)PubMedCrossRef
49.
50.
51.
Wong, R.M.Y., et al.: The relationship between sarcopenia and fragility fracture-a systematic review. Osteoporos. Int. 30(3), 541–553 (2019)PubMedCrossRef
52.
Nasr, R., Watelain, E., Pinti, A., Maalouf, G., Berro, A.J., El Hage, R.: Sarcopenia and hip structure analysis variables in a group of elderly men. J Clin Densitom. 21(2), 312–313 (2018)PubMedCrossRef
Metadata
Title
Influence of Sarcopenia on Bone Health Parameters in a Group of Elderly Lebanese Men
Authors
Amal Antoun
Hayman Saddick
Antonio Pinti
Riad Nasr
Eric Watelain
Eric Lespessailles
Hechmi Toumi
Rawad El Hage
Copyright Year
2020
Book
Bioinformatics and Biomedical Engineering

Print ISBN: 978-3-030-45384-8

Electronic ISBN: 978-3-030-45385-5

Copyright Year: 2020

DOI
https://doi.org/10.1007/978-3-030-45385-5_60

Premium Partner

    Image Credits