2007 | OriginalPaper | Chapter
Informational Structure of Agrobacterium Tumefaciens C58 Genome
Authors : Zhihua Liu, Xiao Sun
Published in: Life System Modeling and Simulation
Publisher: Springer Berlin Heidelberg
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Base-base correlation (BBC) method, based on information theory, translates a DNA sequence into a 16-dimensional vector. It has proven quite effective in distinguishing various functional regions on one chromosome. In this study, we explore the potential use of distinguishing different chromosomes within one species, with particular emphasis on Agrobacterium tumefaciens strain C58. Our findings show that BBC method could effectively distinguish informational structure of Agrobacterium tumefaciens strain C58 genomes. In conclusion, BBC provides a new methodology in post-genome informatics and its applications could be further explored in the further.