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2018 | OriginalPaper | Chapter

Investigation of Glucose-Insulin Model Efficacy for Diabetes Patient in the ICU

Authors : Athirah Abdul Razak, Asma Abu-Samah, Normy N. Razak, Nurhamim Ahamad, Fatanah M. Suhaimi , Ummu K. Jamaludin, Azrina Md Ralib, M. B. Mat-Nor

Published in: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences

Publisher: Springer Singapore

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Abstract

This paper investigates the inter-relationship of blood glucose (BG) model fitting error percentage for both diabetic and non-diabetic patient’s status with ICING glucose-insulin model efficacy. Data were taken from 132 critically ill patients admitted in ICU of Hospital Tunku Ampuan Afzan (HTAA), Kuantan, Malaysia. The BG fitting error results are important to determine the efficacy and safety of chosen glucose-insulin model-based. Analysis results of per-patient and by-cohort were used to suggest whether diabetes is an influential factor for model BG fitting error efficacy. For diabetic per-patient and by-cohort, median model fit error are 0.29 and 0.31% respectively Meanwhile, for non-diabetic per-patient and by-cohort model fit error are 0.27 and 0.29% respectively. In conclusion, results demonstrated no significant difference between diabetic and non-diabetic patient in model fitting error. Thus, ICING model may be used to deliver real time model-based insulin therapy whether patient is diabetic or non-diabetic.

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Footnotes
1
UNITEN is the Universiti Tenaga Nasional, Malaysia.
 
2
IIUM is the International University University Medical, Malaysia.
 
3
UMP is the Universiti Malaysia Pahang, Malaysia.
 
4
USM is the Universiti Sains Malaysia, Malaysia.
 
5
UC is the University of Canterbury, New Zealand.
 
Literature
1.
go back to reference Hui, M., Kumar, A., Adams, G.G.: Protocol-directed insulin infusion sliding scales improve perioperative hyperglycaemia in critical care. Perioper. Med. 1, 7 (2012)CrossRef Hui, M., Kumar, A., Adams, G.G.: Protocol-directed insulin infusion sliding scales improve perioperative hyperglycaemia in critical care. Perioper. Med. 1, 7 (2012)CrossRef
2.
go back to reference Wu, C.H.: A patient-centered self-care support system for diabetics. In: Proceedings of 11th IEEE International Conference on E-bus Engineering (ICEBE 2014), Including 10th Workshop on Service Oriented Applications Integration and Collaboration (SOAIC 2014), 1st Workhop on E-Commerce Engineering (ECE 2014), pp. 298–302 (2014) Wu, C.H.: A patient-centered self-care support system for diabetics. In: Proceedings of 11th IEEE International Conference on E-bus Engineering (ICEBE 2014), Including 10th Workshop on Service Oriented Applications Integration and Collaboration (SOAIC 2014), 1st Workhop on E-Commerce Engineering (ECE 2014), pp. 298–302 (2014)
3.
go back to reference Schlussel, A.T., Holt, D.B., Crawley, E., Lustik, M.B., Wade, C.E., Uyehara, C.F.: Effect of diabetes mellitus on outcomes of hyperglycemia in a mixed medical surgical intensive care unit. J. Diabetes Sci. Technol. 5(3), 731–740 (2011)CrossRef Schlussel, A.T., Holt, D.B., Crawley, E., Lustik, M.B., Wade, C.E., Uyehara, C.F.: Effect of diabetes mellitus on outcomes of hyperglycemia in a mixed medical surgical intensive care unit. J. Diabetes Sci. Technol. 5(3), 731–740 (2011)CrossRef
4.
go back to reference Yamamoto, C., Furutani, E., Sumi, S.: Mathematical model of postprandial glucose-insulin metabolism in insulin dependent diabetics with subcutaneous and intravenous insulin administration routes. In: SICE Annual Conference 2011, pp. 2648–2653 (2011) Yamamoto, C., Furutani, E., Sumi, S.: Mathematical model of postprandial glucose-insulin metabolism in insulin dependent diabetics with subcutaneous and intravenous insulin administration routes. In: SICE Annual Conference 2011, pp. 2648–2653 (2011)
5.
go back to reference Marmarelis, V., Mitsis, G., Daskalaki, E., Diem, P., Mougiakakou, S.: Data-Driven Modeling for Diabetes Diagnosis and Treatment, pp. 91–116. Springer, Berlin Marmarelis, V., Mitsis, G., Daskalaki, E., Diem, P., Mougiakakou, S.: Data-Driven Modeling for Diabetes Diagnosis and Treatment, pp. 91–116. Springer, Berlin
6.
go back to reference Evans, A., Shaw, G.M., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C.G., Pfeifer, L., Penning, S., Suhaimi, F., Signal, M., Desaive, T., Chase, J.G.: “Pilot proof of concept clinical trials of Stochastic Targeted (STAR) glycemic control. Ann. Intensive Care 1(1), 38 (2011)CrossRef Evans, A., Shaw, G.M., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C.G., Pfeifer, L., Penning, S., Suhaimi, F., Signal, M., Desaive, T., Chase, J.G.: “Pilot proof of concept clinical trials of Stochastic Targeted (STAR) glycemic control. Ann. Intensive Care 1(1), 38 (2011)CrossRef
7.
go back to reference Benyo, B., Illyes, A., Nemedi, N.S., Le Compte, A.J., Havas, A., Kovacs, L., Fisk, L., Shaw, G.M., Chase, J.G.: Pilot study of the SPRINT glycemic control protocol in a Hungarian medical intensive care unit. J. Diabetes Sci. Technol. 6(6), 1464–1477 (2012)CrossRef Benyo, B., Illyes, A., Nemedi, N.S., Le Compte, A.J., Havas, A., Kovacs, L., Fisk, L., Shaw, G.M., Chase, J.G.: Pilot study of the SPRINT glycemic control protocol in a Hungarian medical intensive care unit. J. Diabetes Sci. Technol. 6(6), 1464–1477 (2012)CrossRef
8.
go back to reference Lin, J., Chase, J.G., Shaw, G.M., Lotz, T.F., Hann, C.E., Doran, C.V., Lee, D.S.: Long Term Verification of Glucose-Insulin Regulatory System Model Dynamics, pp. 758–761 (2004) Lin, J., Chase, J.G., Shaw, G.M., Lotz, T.F., Hann, C.E., Doran, C.V., Lee, D.S.: Long Term Verification of Glucose-Insulin Regulatory System Model Dynamics, pp. 758–761 (2004)
9.
go back to reference Lin, J., Razak, N.N., Pretty, C.G., Le Compte, A., Docherty, P., Parente, J.D., Shaw, G.M., Hann, C.E., Geoffrey Chase, J.: A physiological intensive control insulin-nutrition-glucose (ICING) model validated in critically ill patients”. Comput. Methods Programs Biomed. 102(2), 192–205 (2011)CrossRef Lin, J., Razak, N.N., Pretty, C.G., Le Compte, A., Docherty, P., Parente, J.D., Shaw, G.M., Hann, C.E., Geoffrey Chase, J.: A physiological intensive control insulin-nutrition-glucose (ICING) model validated in critically ill patients”. Comput. Methods Programs Biomed. 102(2), 192–205 (2011)CrossRef
10.
go back to reference Hann, C.E., Chase, J.G., Lin, J., Lotz, T., Doran, C.V., Shaw, G.M.: Integral-based parameter identification for long-term dynamic verification of a glucose-insulin system model. Comput. Methods Programs Biomed. 77(3), 259–270 (2005)CrossRef Hann, C.E., Chase, J.G., Lin, J., Lotz, T., Doran, C.V., Shaw, G.M.: Integral-based parameter identification for long-term dynamic verification of a glucose-insulin system model. Comput. Methods Programs Biomed. 77(3), 259–270 (2005)CrossRef
11.
go back to reference Huang, C.H., Chen, T.H., Ng, K.L.: Graph theory and stability analysis of protein complex interaction networks. IET Syst. Biol. 10(2), 64–75 (2016)CrossRef Huang, C.H., Chen, T.H., Ng, K.L.: Graph theory and stability analysis of protein complex interaction networks. IET Syst. Biol. 10(2), 64–75 (2016)CrossRef
12.
go back to reference Ahamad, N., Razak, N., Pretty, C., Chase, G.: Efficacy and safety of SPRINT and STAR protocol on malaysian critically-ill patients. In: IEEE EMBS Conference on Biomedical Engineering and Science, pp. 370–375 (2016) Ahamad, N., Razak, N., Pretty, C., Chase, G.: Efficacy and safety of SPRINT and STAR protocol on malaysian critically-ill patients. In: IEEE EMBS Conference on Biomedical Engineering and Science, pp. 370–375 (2016)
13.
go back to reference Jamaludin, U.K., Dzaharudin, F., Razak, N.N.A.: Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. In: IEEE EMBS Conference on Biomedical Engineering and Science, pp. 193–198 (2016) Jamaludin, U.K., Dzaharudin, F., Razak, N.N.A.: Performance of STAR virtual trials for diabetic and non-diabetic in HTAA intensive care unit. In: IEEE EMBS Conference on Biomedical Engineering and Science, pp. 193–198 (2016)
14.
go back to reference Razak, A.A., Razak, N.N., Suhaimi, F.M., Jamaluddin, U.: Efficacy of Glucose-Insulin Model for Sepsis Patients, pp. 1–5 (2014) Razak, A.A., Razak, N.N., Suhaimi, F.M., Jamaluddin, U.: Efficacy of Glucose-Insulin Model for Sepsis Patients, pp. 1–5 (2014)
Metadata
Title
Investigation of Glucose-Insulin Model Efficacy for Diabetes Patient in the ICU
Authors
Athirah Abdul Razak
Asma Abu-Samah
Normy N. Razak
Nurhamim Ahamad
Fatanah M. Suhaimi
Ummu K. Jamaludin
Azrina Md Ralib
M. B. Mat-Nor
Copyright Year
2018
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-7554-4_31