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Published in:
2015 | OriginalPaper | Chapter
Mean Aneurysm Flow Amplitude Ratio Comparison between DSA and CFD
Authors : Fred van Nijnatten, Odile Bonnefous, Hernan G. Morales, Thijs Grünhagen, Roel Hermans, Olivier Brina, Vitor Mendes Pereira, Daniel Ruijters
Published in: Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2015
Publisher: Springer International Publishing
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The Mean Aneurysm Flow Amplitude ratio (MAFA-ratio) has been proposed to evaluate the efficacy of flow diverting stents during minimally invasive intracranial aneurysm treatment. A method has been described for calculating the MAFA-ratio on high frame-rate digital subtraction angiography (DSA) acquisitions using an optical flow algorithm. In this article we have generated computational fluid dynamics (CFD) simulations using six distinct aneurysms and computed the MAFA-ratios based on these data. Furthermore, the simulations have been used to create virtual angiograms, in order to calculate the MAFA-ratios using the DSA approach. An analysis of the MAFAratios generated by both methods shows that there is a monotone increasing relation between the DSA and CFD based ratios, albeit without a slope being identity. Overall, it can be concluded that the DSA-based ratio is a predictor for the magnitude of aneurysm flow reduction, i.e., for the efficacy of flow diverting stents.