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2024 | OriginalPaper | Chapter

Mehrstufige kontinuierliche Durchflussprozesse zur Herstellung von heterocyclischen Wirkstoffen

Authors : Romaric Gérardy, Jean-Christophe M. Monbaliu

Published in: Flow-Chemie für die Synthese von Heterocyclen

Publisher: Springer International Publishing

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Zusammenfassung

Die Durchflusschemie hat viele faszinierende Aspekte, von denen die Umsetzung komplexer mehrstufiger Prozesse in einem ununterbrochenen fluidischen Netzwerk wohl die herausforderndste ist. Dieses Dokument bietet einen gründlichen Überblick über einige der repräsentativsten Beispiele für mehrstufige kontinuierliche Durchflussstrategien im spezifischen Kontext der Herstellung heterocyclischer aktiver Pharmazeutika. Ausgewählte Beispiele, die die Umsetzung mehrstufiger Sequenzen betonen, einschließlich verschiedener Kombinationen chemischer Transformationen, Reinigungen oder Inline-Analysen, werden diskutiert.

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Metadata
Title
Mehrstufige kontinuierliche Durchflussprozesse zur Herstellung von heterocyclischen Wirkstoffen
Authors
Romaric Gérardy
Jean-Christophe M. Monbaliu
Copyright Year
2024
DOI
https://doi.org/10.1007/978-3-031-51912-3_1