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Published in:
Structural and Mechanical Characterization of Supported Model Membranes by AFM Read chapter Read first chapter

2019 | OriginalPaper | Chapter

Modeling of Cell Membrane Systems

Author : Tuğba Arzu Özal İldeniz

Published in: Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

Publisher: Springer International Publishing

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Abstract

The mechanisms that take place in or through cell membranes are vitally important for all living organisms. The molecules embedded in or associated to membranes, such as transmembrane proteins, behave dynamically to perform their functions. Although experimental techniques have improved considerably in recent decades, when combined with computational means of modeling, they reveal secrets behind the mechanisms related to membrane systems. The resolution of the structures of membrane proteins has become trivial recently using computerized prediction tools. The worldwide accumulation of structural data in databases enables the application of in-silico methodologies. Simulations, together with the various lipid membrane models, provide information through the dynamic exploration of conformational space. In this chapter, the basics of modeling are discussed, with a focus on molecular dynamic modeling methodology. In addition to modeling, visualization and analysis tools are also mentioned.

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previous chapter Asymmetric Model Membranes: Frontiers and Challenges
next chapter Molecular Dynamics Studies of Nanoparticle Transport Through Model Lipid Membranes
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Metadata
Title
Modeling of Cell Membrane Systems
Author
Tuğba Arzu Özal İldeniz
Copyright Year
2019
Book
Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

Print ISBN: 978-3-030-11595-1

Electronic ISBN: 978-3-030-11596-8

Copyright Year: 2019

DOI
https://doi.org/10.1007/978-3-030-11596-8_4

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