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2013 | OriginalPaper | Chapter

6. Nanotechnology to Prevent Electron Transfer

Author : Sandro Carrara

Published in: Bio/CMOS Interfaces and Co-Design

Publisher: Springer New York

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Abstract

We saw in Chap.​ 5 different mechanisms of molecular assembly onto surfaces. These mechanisms also play a role in molecular assembly onto Bio/CMOS surfaces. In this chapter, we will show how to use DNA short oligonucleotides or antibodies (Chap.​ 3) to develop Bio/CMOS interfaces to sense DNA hybridization or to provide antigen detection. The chapter also shows how different kinds of adsorption mechanisms and different kinds of DNA monolayers produce different Bio/CMOS interfaces with completely different electrical behaviors. In particular, the chapter shows how to use special alkanethiols to improve the quality of these probe surfaces on the nanoscale. We will see that the nanoscale quality of the Bio/CMOS interface is so important that, in some cases, this means we can have the sensing or if we fail on that.

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previous chapter Surface Immobilization of Probes
next chapter Bio/CMOS Interfaces for Label-Free Capacitance Sensing
Literature
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Carrara S, Benini L, Bhalla V, Stagni C, Ferretti A, Cavallini A, Riccò B, Samorì B (2009) New insights for using self-assembly materials to improve the detection stability in label-free DNA-chip and immuno-sensors. Biosens Bioelectron 24:3425–3429CrossRef
Metadata
Title
Nanotechnology to Prevent Electron Transfer
Author
Sandro Carrara
Copyright Year
2013
Publisher
Springer New York
Book
Bio/CMOS Interfaces and Co-Design

Print ISBN: 978-1-4614-4689-7

Electronic ISBN: 978-1-4614-4690-3

Copyright Year: 2013

DOI
https://doi.org/10.1007/978-1-4614-4690-3_6