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Published in:
2009 | OriginalPaper | Chapter
Organizational Structure of the Transcriptional Regulatory Network of Yeast: Periodic Genes
Authors : Frank Emmert-Streib, Matthias Dehmer
Published in: Complex Sciences
Publisher: Springer Berlin Heidelberg
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In this paper we investigate the organizational structure of the transcriptional regulatory network of
S. cerevisiae
with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.