Advertisement
Published in:
2007 | OriginalPaper | Chapter
Predicting Functional Protein-Protein Interactions Based on Computational Methods
Authors : Luwen Zhang, Wu Zhang
Published in: Life System Modeling and Simulation
Publisher: Springer Berlin Heidelberg
Activate our intelligent search to find suitable subject content or patents.
Select sections of text to find matching patents with Artificial Intelligence. powered by
Select sections of text to find additional relevant content using AI-assisted search. powered by
Protein-protein interactions play a crucial role in the cellular process. In recent years, yet new experimental techniques have been developed to discover the protein-protein interaction networks, the accuracy and coverage has still proven to be limited. Computational approaches come into being essential both to assist in the design and validation of experimental studies and for the prediction of interacted proteins. This paper presents a survey of the major computational methods for detecting protein-protein interactions, and expatiates on their key contribution by introducing the experimental methods, the typical computational methods and the improvement over them in turn.