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2011 | OriginalPaper | Chapter

Recent Advances in the Synthesis of Morphine and Related Alkaloids

Author : Noritaka Chida

Published in: Chemistry of Opioids

Publisher: Springer Berlin Heidelberg

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Abstract

Morphine, an alkaloid isolated from the opium poppy, has been widely used as an analgesic, and has been a fascinating synthetic target of organic chemists. After the first total synthesis reported in 1952, a number of synthetic studies toward morphine have been reported, and findings obtained in such studies have greatly contributed to the progress of synthetic organic chemistry as well as medicinal chemistry. This review provides an overview of recent studies toward the total synthesis of morphine and related alkaloids. Work reported in the literature since 2004 will be reviewed.

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next chapter Opioids in Preclinical and Clinical Trials
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Metadata
Title
Recent Advances in the Synthesis of Morphine and Related Alkaloids
Author
Noritaka Chida
Copyright Year
2011
Publisher
Springer Berlin Heidelberg
Book
Chemistry of Opioids

Print ISBN: 978-3-642-18106-1

Electronic ISBN: 978-3-642-18107-8

Copyright Year: 2011

DOI
https://doi.org/10.1007/128_2010_73