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Published in:
Oligooxopiperazines as Topographical Helix Mimetics Read chapter Read first chapter

2017 | OriginalPaper | Chapter

Recent Studies on Gramicidin S Analog Structure and Antimicrobial Activity

Authors : Sudip Pal, Uttam Ghosh, Ravi Sankar Ampapathi, Tushar Kanti Chakraborty

Published in: Peptidomimetics II

Publisher: Springer International Publishing

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Abstract

Gramicidin S, the most notable example of cationic antimicrobial peptides (CAPs), has remained in the forefront of worldwide research for development of new antibiotics for over seven decades now. Hundreds of papers have been published over the years on this molecule and its numerous analogs, delineating their structures and biological activities with an aim to achieve selective antimicrobial activities with reduced cytotoxicity for potential therapeutic applications. The present review attempts to capture the essence of some of the recent studies with the aims to chronicle the journey traversed by this fascinating molecule so far and to decipher what is needed for future success.

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Metadata
Title
Recent Studies on Gramicidin S Analog Structure and Antimicrobial Activity
Authors
Sudip Pal
Uttam Ghosh
Ravi Sankar Ampapathi
Tushar Kanti Chakraborty
Copyright Year
2017
Book
Peptidomimetics II

Print ISBN: 978-3-319-49123-3

Electronic ISBN: 978-3-319-49124-0

Copyright Year: 2017

DOI
https://doi.org/10.1007/7081_2015_188