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2016 | OriginalPaper | Chapter

Retinal Nerve Fiber Layer Analysis in Digital Fundus Images: Application to Early Glaucoma Diagnosis

Authors : Dharmanna Lamani, T. C. Manjunath, M. Mahesh, Y. S. Nijagunarya

Published in: Proceedings of the International Conference on Recent Cognizance in Wireless Communication & Image Processing

Publisher: Springer India

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Abstract

Glaucoma is a second biggest eye disease which leads to permanent vision loss. The present day glaucoma diagnosis includes analysis of cup-to-disk ratio and detection of retinal nerve fiber layer (RNFL) loss. Glaucoma detection using cup-to-disk ratio approach is possible only after 40 % of vision loss. Also, OCT instruments are not widely available in all hospitals due to the cost factor, thereby making them a costly approach. In this paper, fundus images are considered for texture property analysis. Texture properties of RNFL region are analyzed using image-based fractal dimension (FD) feature and gray level co-occurrence matrix method (GLCM). Positive correlation coefficient is achieved for FD and contrast property of GLCM. Such analysis of texture property involving RNFL on fundus images lead to low cost and early diagnosis of glaucoma.

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Literature
1.
go back to reference Odstrcilik, J., Kolar, R., Tornow, R.P., Jan, J., Budai, A., Mayer, M., Vodakova, M., Laemmer, R., Lamos, M., Kuna, Z., Gazarek, Z., Kubena, T., Cernosek, P., Ronzhina, M.: Thickness related textural properties of retinal nerve fiber layer in color fundus images. Comput. Med. Imaging Graph. 38, 508–516 (2014) Odstrcilik, J., Kolar, R., Tornow, R.P., Jan, J., Budai, A., Mayer, M., Vodakova, M., Laemmer, R., Lamos, M., Kuna, Z., Gazarek, Z., Kubena, T., Cernosek, P., Ronzhina, M.: Thickness related textural properties of retinal nerve fiber layer in color fundus images. Comput. Med. Imaging Graph. 38, 508–516 (2014)
2.
go back to reference Burana-Anusorn, C., Kongprawechnon, W., Kondo, T., Sintuwong, S., Tungpimolrut, K.: Image processing techniques for glaucoma detection using the cup-to-disc ratio. Thammasat Int. J. Sci. Technol. 18(1) (2013) Burana-Anusorn, C., Kongprawechnon, W., Kondo, T., Sintuwong, S., Tungpimolrut, K.: Image processing techniques for glaucoma detection using the cup-to-disc ratio. Thammasat Int. J. Sci. Technol. 18(1) (2013)
3.
go back to reference Annadhason, A.: Methods of fractal dimension computation. In: IRACST—International Journal of Computer Science and Information Technology & Security (IJCSITS) vol. 2, No. 1 (2012). ISSN: 2249-9555 Annadhason, A.: Methods of fractal dimension computation. In: IRACST—International Journal of Computer Science and Information Technology & Security (IJCSITS) vol. 2, No. 1 (2012). ISSN: 2249-9555
4.
go back to reference Mayer, M.A., Hornegger, J., Mardin, C.Y., Tornow, R.P.: Retinal nerve fiber layer segmentation on FD-OCT scans of normal subjects and glaucoma patients. Biomed. Opt. Express 1(5), 1358 (2010) Mayer, M.A., Hornegger, J., Mardin, C.Y., Tornow, R.P.: Retinal nerve fiber layer segmentation on FD-OCT scans of normal subjects and glaucoma patients. Biomed. Opt. Express 1(5), 1358 (2010)
5.
go back to reference Bock, Rüdiger, Meier, Jörg, Nyúl, László G., Hornegger, Joachim, Michelson, Georg: Glaucoma risk index: automated glaucoma detection from color fundus images. Med. Image Anal. 14, 471–481 (2010)CrossRef Bock, Rüdiger, Meier, Jörg, Nyúl, László G., Hornegger, Joachim, Michelson, Georg: Glaucoma risk index: automated glaucoma detection from color fundus images. Med. Image Anal. 14, 471–481 (2010)CrossRef
6.
go back to reference Huang, X.-R., Knighton, R.W., Shestopalov, V.: Quantifying retinal nerve fiber layer thickness in whole-mounted retina. Exp. Eye Res. 83, 1096e−1101 (2006) Huang, X.-R., Knighton, R.W., Shestopalov, V.: Quantifying retinal nerve fiber layer thickness in whole-mounted retina. Exp. Eye Res. 83, 1096e−1101 (2006)
7.
go back to reference Park, J., Kemp, N.J., Zaatari, H.N., Milner, T.E., Rylander, H. G.: Analysis of phase retardation in the primate retinal nerve fiber layer by polarization sensitive optical coherence tomography. In: Proceedings of the 25* Annual International Conference of the IEEE EMBS, Cancun, Mexico, 17−21 Sept 2003 Park, J., Kemp, N.J., Zaatari, H.N., Milner, T.E., Rylander, H. G.: Analysis of phase retardation in the primate retinal nerve fiber layer by polarization sensitive optical coherence tomography. In: Proceedings of the 25* Annual International Conference of the IEEE EMBS, Cancun, Mexico, 17−21 Sept 2003
8.
go back to reference Lu, S., Cheung, C.Y., Liu, J., Lim, J.H., Leung, C.K., Wong, T.Y.: Automated layer segmentation of optical coherence tomography images. IEEE Trans. Biomed. Eng. 57(10) (2010) Lu, S., Cheung, C.Y., Liu, J., Lim, J.H., Leung, C.K., Wong, T.Y.: Automated layer segmentation of optical coherence tomography images. IEEE Trans. Biomed. Eng. 57(10) (2010)
9.
go back to reference Zhu, H., Crabb, D.P., Schlottmann, P.G., Wollstein, G., Garway-Heath, D.F.: Aligning scan acquisition circles in optical coherence tomography images of the retinal nerve fibre layer. IEEE Trans. Med. Imaging 30(6) (2011) Zhu, H., Crabb, D.P., Schlottmann, P.G., Wollstein, G., Garway-Heath, D.F.: Aligning scan acquisition circles in optical coherence tomography images of the retinal nerve fibre layer. IEEE Trans. Med. Imaging 30(6) (2011)
10.
go back to reference Acharya, U.R., Dua, S., Du, X., Vinitha Sree, S., Chua, C.K.: Automated diagnosis of glaucoma using texture and higher order spectra features. IEEE Trans. Inf. Technol. Biomed. 15(3) (2011) Acharya, U.R., Dua, S., Du, X., Vinitha Sree, S., Chua, C.K.: Automated diagnosis of glaucoma using texture and higher order spectra features. IEEE Trans. Inf. Technol. Biomed. 15(3) (2011)
11.
go back to reference Gazarek, J., Jan, J., Kolar, R., Odstrcilik, J.: Retinal nerve fibre layer detection in fundus camera images compared to results from optical coherence tomography. In: International Conference on Image Information Processing (ICIIP 2011) (2011) Gazarek, J., Jan, J., Kolar, R., Odstrcilik, J.: Retinal nerve fibre layer detection in fundus camera images compared to results from optical coherence tomography. In: International Conference on Image Information Processing (ICIIP 2011) (2011)
12.
go back to reference Lamani, D., Manjunath, T.C., Ramegowda: Cup-disk segmentation and fractal dimension to detect glaucomatous eyes. In: National Conference on Current Trends in Research and Technology (CRT-13), Sponsored by IET (The Institute of Engineering & Technology, UK), SDMIT, Ujire, South Kanara, Karnataka, India, 27−28 Sep 2013 Lamani, D., Manjunath, T.C., Ramegowda: Cup-disk segmentation and fractal dimension to detect glaucomatous eyes. In: National Conference on Current Trends in Research and Technology (CRT-13), Sponsored by IET (The Institute of Engineering & Technology, UK), SDMIT, Ujire, South Kanara, Karnataka, India, 27−28 Sep 2013
13.
go back to reference Lamani, D., Manjunath, T.C., Ramegowda: Fractal dimension with object rotation: a case study with glaucoma eye. In: 5th IEEE International Conference on Signal and Image Processing (ICSIP-2014), BNMIT, Bangalore, Karnataka, India, 978-0-7695-5100-5/13 $31.00 © 2013 IEEE DOI 10.1109/ICSIP.2014.22, ISBN: 978-0-7695-5100-5, Paper No. ICSIP-31, Session-Medical Image Processing, pp. 111−116, 8−10 Jan 2014 Lamani, D., Manjunath, T.C., Ramegowda: Fractal dimension with object rotation: a case study with glaucoma eye. In: 5th IEEE International Conference on Signal and Image Processing (ICSIP-2014), BNMIT, Bangalore, Karnataka, India, 978-0-7695-5100-5/13 $31.00 © 2013 IEEE DOI 10.​1109/​ICSIP.​2014.​22, ISBN: 978-0-7695-5100-5, Paper No. ICSIP-31, Session-Medical Image Processing, pp. 111−116, 8−10 Jan 2014
14.
go back to reference Lamani, D., Manjunath, T.C.: Automatic detection of diabetes retinopathy through image feature power spectral fractal dimension. In: 8th Elsevier International Conference on Image and Signal Processing (ICISP-2014), UVCE, Bangalore, Karnataka, India, Paper ID : ICISP-357, Reference No.: 357I-S, 25−26 July 2014 Lamani, D., Manjunath, T.C.: Automatic detection of diabetes retinopathy through image feature power spectral fractal dimension. In: 8th Elsevier International Conference on Image and Signal Processing (ICISP-2014), UVCE, Bangalore, Karnataka, India, Paper ID : ICISP-357, Reference No.: 357I-S, 25−26 July 2014
15.
go back to reference Kersey, T., Clement, C.I., Bloom, P., Cordeiro, M.F.: New trends in glaucoma risk, diagnosis & management. Indian J Med Res 137, 659−668 (2013) Kersey, T., Clement, C.I., Bloom, P., Cordeiro, M.F.: New trends in glaucoma risk, diagnosis & management. Indian J Med Res 137, 659−668 (2013)
16.
go back to reference Kolar, R., Tornow, R.P., Jan, Laemmer, R., Odstrcilik, J., Mayer, M.A.: Analysis of visual appearance of retinal nerve fibers in high resolution fundus images: a study on normal subjects. Comput. Math. Methods Med. 2013, Article ID 134543, 1−10 (2013) Kolar, R., Tornow, R.P., Jan, Laemmer, R., Odstrcilik, J., Mayer, M.A.: Analysis of visual appearance of retinal nerve fibers in high resolution fundus images: a study on normal subjects. Comput. Math. Methods Med. 2013, Article ID 134543, 1−10 (2013)
17.
go back to reference Kolar, Radim, Jan, Jiri: Detection of glaucomatous eye via color fundus images using fractal dimensions. Radio Eng. 17(3), 109–114 (2008) Kolar, Radim, Jan, Jiri: Detection of glaucomatous eye via color fundus images using fractal dimensions. Radio Eng. 17(3), 109–114 (2008)
18.
go back to reference Kolar, R., Vacha, P.: Texture analysis of the retinal nerve fiber layer in fundus images via Markov random fields. In: IFMBE Proceedings 25/XI, pp. 247–250 (2009) Kolar, R., Vacha, P.: Texture analysis of the retinal nerve fiber layer in fundus images via Markov random fields. In: IFMBE Proceedings 25/XI, pp. 247–250 (2009)
19.
go back to reference Cheung, C.Y.L., Leung, C.K.: A practical guide for interpretation of optical coherence tomography retinal nerve fiber layer measurement. J. Current Glaucoma Pract. 1(3), 9–13 (2009) Cheung, C.Y.L., Leung, C.K.: A practical guide for interpretation of optical coherence tomography retinal nerve fiber layer measurement. J. Current Glaucoma Pract. 1(3), 9–13 (2009)
20.
go back to reference Lamani, D., Manjunath, T.C., Kulkarni, U.P.: Automated detection of neovascular glaucoma through fractal dimension method. Int. J. Comput. Sci. Inf. Technol. 5(4), 5252−5257 (2014). ISSN: 0975-9646 Lamani, D., Manjunath, T.C., Kulkarni, U.P.: Automated detection of neovascular glaucoma through fractal dimension method. Int. J. Comput. Sci. Inf. Technol. 5(4), 5252−5257 (2014). ISSN: 0975-9646
Metadata
Title
Retinal Nerve Fiber Layer Analysis in Digital Fundus Images: Application to Early Glaucoma Diagnosis
Authors
Dharmanna Lamani
T. C. Manjunath
M. Mahesh
Y. S. Nijagunarya
Copyright Year
2016
Publisher
Springer India
DOI
https://doi.org/10.1007/978-81-322-2638-3_8