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Published in:
2013 | OriginalPaper | Chapter
Segmentation of Cells with Partial Occlusion and Part Configuration Constraint Using Evolutionary Computation
Authors : Masoud S. Nosrati, Ghassan Hamarneh
Published in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013
Publisher: Springer Berlin Heidelberg
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We propose a method for targeted segmentation that identifies and delineates only those spatially-recurring objects that conform to specific geometrical, topological and appearance priors. By adopting a “tribes”-based, global genetic algorithm, we show how we incorporate such priors into a faithful objective function unconcerned about its convexity. We evaluated our framework on a variety of histology and microscopy images to segment potentially overlapping cells with complex topology. Our experiments confirmed the generality, reproducibility and improved accuracy of our approach compared to competing methods.