2013 | OriginalPaper | Chapter
Self-gated Radial MRI for Respiratory Motion Compensation on Hybrid PET/MR Systems
Authors : Robert Grimm, Sebastian Fürst, Isabel Dregely, Christoph Forman, Jana Maria Hutter, Sibylle I. Ziegler, Stephan Nekolla, Berthold Kiefer, Markus Schwaiger, Joachim Hornegger, Tobias Block
Published in: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2013
Publisher: Springer Berlin Heidelberg
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Accurate localization and uptake quantification of lesions in the chest and abdomen using PET imaging is challenging due to the respiratory motion during the exam. The advent of hybrid PET/MR systems offers new ways to compensate for respiratory motion without exposing the patient to additional radiation. The use of self-gated reconstructions of a 3D radial stack-of-stars GRE acquisition is proposed to derive a high-resolution MRI motion model. The self-gating signal is used to perform respiratory binning of the simultaneously acquired PET raw data. Matching
μ
-maps are generated for every bin, and post-reconstruction registration is performed in order to obtain a motion-compensated PET volume from the individual gates. The proposed method is demonstrated in-vivo for three clinical patients. Motion-corrected reconstructions are compared against ungated and gated PET reconstructions. In all cases, motion-induced blurring of lesions in the liver and lung was substantially reduced, without compromising SNR as it is the case for gated reconstructions.