2005 | OriginalPaper | Chapter
Separation and Isolation Techniques
Published in: Bioactive Marine Natural Products
Publisher: Springer Netherlands
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The chapter deals with the separation and isolation techniques of bioactive compounds of marine organisms. The ion-exchange chromatography, reverse-phase columns, high/medium pressure chromatography on porous materials, combination of ion exchange and size-exclusion chromatography, and bioassay directed fractionation have been discussed. Besides, isolation procedures of some bioactive amino acids, peptides, nucleosides, cytokinins, alkaloids and toxins have been given.