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Potential and Challenges of Graphene in Medicine Read chapter Read first chapter

2016 | OriginalPaper | Chapter

Stem Cells Commitment on Graphene-Based Scaffolds

Authors : Maurizio Buggio, Marco Tatullo, Stefano Sivolella, Chiara Gardin, Letizia Ferroni, Eitan Mijiritsky, Adriano Piattelli, Barbara Zavan

Published in: Graphene-based Materials in Health and Environment

Publisher: Springer International Publishing

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Abstract

In the last years, a rapid development in production, and functionalization of graphene give rise to several products that have shown great potentials in many fields, such as nanoelectronics, energy technology, sensors, and catalysis. In this context we should not forget the biomedical application of graphene that became a new area with outstanding potential. The first study on graphene for biomedical applications has been performed by Dai in 2008 that reported the use of graphene oxide as an efficient nanocarrier for drug delivery. This pioneristic study opened the doors for the use of graphene in widespread biomedical applications such as drug/gene delivery, biological sensing and imaging, antibacterial materials, but also as biocompatible scaffold for cell culture and tissue engineering. The application of graphene-based scaffolds for tissue engineering applications is confirmed by the many exciting and intriguing literature reports over the last few years, that clearly confirm that graphene and its related substrates are excellent platforms for adhesion, proliferation, and differentiation of various cells such as human Mesenchymal stem cells, human neuronal stem cells, and induced pluripotent stem cells. Since most of the papers on this fields are related to in vitro studies, several future in vivo investigations need to be conducted in order to lead to its utilization as implantable tissue engineering material.

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previous chapter Hybrid Graphene Metallic Nanoparticles for Biodetection
next chapter Graphene: An Emerging Carbon Nanomaterial for Bone Tissue Engineering
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Metadata
Title
Stem Cells Commitment on Graphene-Based Scaffolds
Authors
Maurizio Buggio
Marco Tatullo
Stefano Sivolella
Chiara Gardin
Letizia Ferroni
Eitan Mijiritsky
Adriano Piattelli
Barbara Zavan
Copyright Year
2016
Book
Graphene-based Materials in Health and Environment

Print ISBN: 978-3-319-45637-9

Electronic ISBN: 978-3-319-45639-3

Copyright Year: 2016

DOI
https://doi.org/10.1007/978-3-319-45639-3_4

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