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Published in: Journal of Nanoparticle Research 3/2014

01-03-2014 | Research Paper

Study of gold nanostar@SiO2@CdTeS quantum dots@SiO2 with enhanced-fluorescence and photothermal therapy multifunctional cell nanoprobe

Authors: Naiqiang Yin, Tongtong Jiang, Jing Yu, Jiawei He, Xu Li, Qianpeng Huang, Ling Liu, Xiaoliang Xu, Lixin Zhu

Published in: Journal of Nanoparticle Research | Issue 3/2014

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Abstract

A novel class of cell probe structured as gold nanostar@SiO2@CdTeS quantum dots@SiO2 nanoprobes with multifunctional (MFNPs) fluorescent and photothermal properties were demonstrated. The MFNPs with good homogeneity (129 ± 10 nm) and dispersity were synthesized by a liquid phase method. The fluorescence signal of quantum dots was enhanced in the MFNPs, compared with the pure quantum dots. The vitro study showed that the MFNPs can realize the targeted labeling after functionalized with anti-body. Furthermore, the nanoprobe displays strong surface plasmonic resonance absorbance in the near-infrared region, thus exhibiting an NIR (808 nm)-induced temperature elevation. When cancer cells were cultured with the anti-body linked MFNPs and irradiated by laser, the MFNPs were demonstrated as good candidates for curing cancer cells. Therefore, such a multifunctional probe can be developed as a promising nanosystem that integrates multiple capabilities for effective cancer diagnosis and therapy.

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Metadata
Title
Study of gold nanostar@SiO2@CdTeS quantum dots@SiO2 with enhanced-fluorescence and photothermal therapy multifunctional cell nanoprobe
Authors
Naiqiang Yin
Tongtong Jiang
Jing Yu
Jiawei He
Xu Li
Qianpeng Huang
Ling Liu
Xiaoliang Xu
Lixin Zhu
Publication date
01-03-2014
Publisher
Springer Netherlands
Published in
Journal of Nanoparticle Research / Issue 3/2014
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-014-2306-5

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