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Published in: Optical and Quantum Electronics 4/2023

01-04-2023

Surface microfluidics elements fabrication by CO2-laser writing on glass: challenges and perspectives

Authors: A. G. Bondarenko, A. Ramos-Velazquez, A. V. Shmalko, R. A. Zakoldaev

Published in: Optical and Quantum Electronics | Issue 4/2023

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Abstract

Microfluidic systems have become part of our everyday life, with surface microfluidics occupying its niche in instant diagnostics and point-of-care testing. Implementing surface microfluidics on a large scale appears to be impossible without developing or upgrading manufacturing technologies. Our paper proposes a CO2-laser microtechnology of precise fused silica surface processing. Key microfluidic elements–microchannels, input and deposition reservoirs have been designed, fabricated and tested with picoliter volumes of fluids. Optical transmittance of the elements remains high enough to observe reactions in a microfluidic system by means of optical methods. The above research and its results would contribute to making laser microtechnologies available to a wide range of experimental and commercial users of microfluidics.

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Literature
go back to reference Hülsenberg, D., Harnisch, A., Bismarck, A.: Microstructuring glasses using lasers. Springer (2008)CrossRef Hülsenberg, D., Harnisch, A., Bismarck, A.: Microstructuring glasses using lasers. Springer (2008)CrossRef
go back to reference Li, X., Hofmeister, W., Shen, G., Davis, L., & Daniel, C.: Fabrication and characterization of nanofluidics device using fused silica for single protein molecule detection. Medical Device Materials IV (Proceedings of Materials and Processes for Medical Devices 2007), pp 145–150, ASM International (2008). Li, X., Hofmeister, W., Shen, G., Davis, L., & Daniel, C.: Fabrication and characterization of nanofluidics device using fused silica for single protein molecule detection. Medical Device Materials IV (Proceedings of Materials and Processes for Medical Devices 2007), pp 145–150, ASM International (2008).
go back to reference Smith, M. A., Berry, S., Parameswaran, L., Holtsberg, C., Siegel, N., Lockwood, R.,& Rothschild, M.: Design, simulation, and fabrication of three-dimensional microsystem components using grayscale photolithography. Journal of Micro/Nanolithography, MEMS, and MOEMS (2019). doi: https://doi.org/10.1117/1.JMM.18.4.043507 Smith, M. A., Berry, S., Parameswaran, L., Holtsberg, C., Siegel, N., Lockwood, R.,& Rothschild, M.: Design, simulation, and fabrication of three-dimensional microsystem components using grayscale photolithography. Journal of Micro/Nanolithography, MEMS, and MOEMS (2019). doi: https://​doi.​org/​10.​1117/​1.​JMM.​18.​4.​043507
Metadata
Title
Surface microfluidics elements fabrication by CO2-laser writing on glass: challenges and perspectives
Authors
A. G. Bondarenko
A. Ramos-Velazquez
A. V. Shmalko
R. A. Zakoldaev
Publication date
01-04-2023
Publisher
Springer US
Published in
Optical and Quantum Electronics / Issue 4/2023
Print ISSN: 0306-8919
Electronic ISSN: 1572-817X
DOI
https://doi.org/10.1007/s11082-023-04675-2

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