Skip to main content
Disciplines
Automotive Business IT + Informatics Construction + Real Estate Electrical Engineering + Electronics Energy + Sustainability Insurance + Risk Finance + Banking Management + Leadership Marketing + Sales Mechanical Engineering + Materials
Events
DE
EN
Books
Journals
Topic Page
Marketing
Start single access now
Access for companies
EXTENDED SEARCH
Log in
Top
Journal of Materials Science
Published in: Journal of Materials Science 7/2020

22-11-2019 | Materials for life sciences

Synthesis and physico-chemical properties of poly(N-vinyl pyrrolidone)-based hydrogels with titania nanoparticles

Authors: Olesya Timaeva, Igor Pashkin, Sergey Mulakov, Galina Kuzmicheva, Petr Konarev, Raisa Terekhova, Natalia Sadovskaya, Orsolya Czakkel, Sylvain Prevost

Published in: Journal of Materials Science | Issue 7/2020

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

Poly(N-vinyl pyrrolidone) (PVP)-based hydrogels with titania nanoparticles (TN) were synthesized by the sol–gel method for the first time and were characterized in different states (native, freeze-dried, air-dried to constant weight and ground to powder, or swollen to constant weight in H2O or D2O) by various methods such as wide-angle and small-angle X-ray and neutron scattering, neutron spin-echo (NSE) spectroscopy, and scanning electron microscopy. The static (static polymer–polymer correlation length (mesh size), associates of cross-links and PVP microchains) and dynamic (polymer chain relaxation rate, hydrodynamic polymer–polymer correlation length) structural elements were determined. The incorporation of titania nanoparticles into PVP hydrogel slightly increases the size of structural inhomogeneities (an increase in the static and dynamic polymer–polymer correlation length, the formation of associates of cross-links and PVP chains). Titania nanoparticles have an impact on the microstructure of the composite hydrogel and form associates with sizes from 0.5 to 2 µm attached to PVP hydrogel pore walls. The PVP and TN/PVP hydrogels show a high degree of water swelling. Moreover, the presence of titania nanoparticles in TN/PVP increases the number of water adsorption cycles compared to PVP hydrogel. The high swelling degree, bacteria-resistant and antimicrobial properties against Staphylococcus aureus allow considering NT/PVP hydrogels for medical applications as wound coatings.
previous article Supercooling characteristics of mannitol phase transition system under heterogeneous nucleation
next article The suitability of Synbone® as a tissue analogue in ballistic impacts

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

inform now
Literature
1.
Sen M, Guven O (1998) Prediction of swelling behavior of hydrogels containing diprotic acid moieties. Polymer 39:1165–1172
2.
Nicodemus GD, Bryant SJ (2008) Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue EngPart B Rev 14:149–165
3.
Hoffman AS (2002) Hydrogels for biomedical applications. Adv Drug Deliv Rev 54:3–12
4.
Kamata H, Akagi Y, Kayasuga-Kariya Y, Chung U, Sakai T (2014) “Nonswellable” hydrogel without mechanical hysteresis. Science 343:873–875
5.
Gaharwar AK, Peppas NA, Khademhosseini A (2014) Nanocomposite hydrogels for biomedical applications. Biotechnol Bioeng 111:441–453
6.
7.
Rosiak JM, Rucinska R, Pekala W. U.S. Patent No. 4871490
8.
Rogero SO, Malmonge SM, Lugao AB, Ikeda TI, Miyamaru L, Cruz AS (2003) Biocompatibility study of polymeric biomaterials. Artif Organs 27:424–427
9.
Maher SA, Doty SB, Torzilli PA, Thornton S, Lowman AM, Thomas JD, Warren R, Wright TM (2007) Myers E (2007) Nondegradable hydrogels for the treatment of focal cartilage defects. J Biomed Mater Res 83:145–155
10.
Zheng Y, Huang X, Wang Y, Xu H, Chen X (2009) Performance and characterization of irradiated poly(vinyl alcohol)/polyvinylpyrrolidone composite hydrogels used as cartilages replacement. J Appl Polym Sci 113:736–741
11.
Kirsh YuE (1998) Water soluble poly-N-vinylamides. synthesis and physicochemical properties. Wiley, Chichester
12.
Jiao YP, Liu ZH, Ding S, Li LH, Zhou CR (2006) Preparation of biodegradable crosslinking agents and application in PVP hydrogel. J Appl Polym Sci 101:1515–1521
13.
Benamer S, Mahlous M, Boukrif A, Mansouri B, Larbi YS (2006) Synthesis and characterisation of hydrogels based on poly(vinyl pyrrolidone). Nucl Instr Methods Phys Res B 248:284–290
14.
Ajji Z, Othman I, Rosiak JM (2005) Production of hydrogel wound dressings using gamma radiation. Nucl Instrum Methods Phys Res B 229:375–380
15.
Wang D, Hill DJT, Rasoul F, Whittaker AK (2011) A study of the swelling and model protein release behaviours of radiationformed poly(n-vinyl-2-pyrrolidone-co-acrylic acid) hydrogels. Radiat Phys Chem 80:207–212
16.
Nho Y, Lim Y, An S, Kim Y (2008) Therapeutic hydrogel for atopic dermatitis and preparation method thereof. EP 1 889 608 B1
17.
Darwis D, Hilmy N, Hardiningsih L, Erlinda T (1993) Poly(N-vinylpyrrolidone) hydrogels: 1. Radiation polymerization and crosslinking of N-vinylpyrrolidone. Radiat Phys Chem 42:907–910
18.
Himly N, Darwis D, Hardiningsih L (1993) Poly(n-vinylpyrrolidone) hydrogels: 2. hydrogel composites as wound dressing for tropical environment. Radiat Phys Chem 4:911–914
19.
Erdem A, Metzler D, Cha D, Huang CP (2015) Inhibition of bacteria by photocatalytic nano-TiO2 particles in the absence of light. Int J Environ Sci Technol 12:2987–2996
20.
Huppman T, Yatsenko S, Leonhardt S, Krampe E, Radovanovic I, Bastian M, Wintermantel E (2014) Antimicrobial polymers—The antibacterial effect of photoactivated nano titanium dioxide polymer composites. AIP Conf Proc 1593:440–443
21.
Bodaghi H, Mostofi Y, Oromiehie A, Zamani Z, Ghanbarzadeh B, Costa C, Conte A, Del Nobile MA (2013) Evaluation of the photocatalytic antimicrobial effects of a TiO2 nanocomposite food packaging film by in vitro and in vivo tests. LWT Food Sci Technol 50:702–706
22.
Cao L, Wu X, Wang Q, Wang J (2018) Biocompatible nanocomposite of TiO2 incorporated bi-polymer for articular cartilage tissue regeneration: a facile material. J Photoch Photobio B 178:440–446
23.
Archana D, Singh BK, Dutta J, Dutta PK (2013) In vivo evaluation of chitosan–PVP–titanium dioxide nanocomposite as wound dressing material. Carbohydr Polym 95:530–539
24.
Kuz’micheva GM, Podbel’sky VV, Stepanov AN, Gaynanova AA (2017) Program for processing of diffraction patterns of nanosized and amorphous substances and calculation of the substructure. No. 2017610699
25.
Korneev VN, Shlektarev VA, Zabelin AV, Aul’chenko VM, Tolochko BP, Ariskin NI, Lanina LF, Vazina AA (2012) X-ray stations based on cylindrical zoom lenses for nanostructural investigations using synchrotron radiation. J Surf Invest X-ray Synchrotron Neutron Tech 6:849–864
26.
Huang TC, Toraya H, Blanton TN, Wu Y (1993) X-ray powder diffraction analysis of silver behenate, a possible low-angle diffraction standard. J Appl Cryst 26:180–184
27.
Hammersley AP (1997) FIT2D: an introduction and overview. ESRF97HA02T, France
28.
Konarev PV, Volkov VV, Sokolova AV, Koch MHJ, Svergun DI (2003) PRIMUS: a Windows PC-based system for small-angle scattering data analysis. J Appl Cryst 36:1277–1282
29.
Konarev PV, Petoukhov MV, Volkov VV, Svergun DI (2006) ATSAS 2.1, a program package for small-angle scattering data analysis. J Appl Cryst 39:277–286
30.
Svergun DI (1992) Determination of the regularization parameter in indirect-transform methods using perceptual criteria. J Appl Cryst 25:495–503
31.
Svergun DI, Shtykova EV, Volkov VV, Feigin LA (2011) Small-angle X-ray scattering, synchrotron radiation, and the structure of bio- and nanosystems. Crystallogr Rep 56:725–750
32.
33.
Richard D, Ferrand M, Kearley GJ (1996) Analysis and visualisation of neutron-scattering data. J Neutron Res 4:33–39
34.
Brebler I, Kohlbrecher J, Thunemann AF (2015) SASfit: a tool for small-angle scattering data analysis using a library of analytical expressions. J Appl Cryst 48:1587–1598
35.
Mezei F, Pappas C, Gutberlet T (2003) Neutron spin echo spectroscopy—basics, trends and applications. Springer, Heidelberg
36.
Kim SH, Chu CC (2000) Pore structure analysis of swollen dextran-methacrylate hydrogels by SEM and mercury intrusion porosimetry. J Biomed Mater Res (Appl Biomater) 53:258–266
37.
Teng J, Bates S, Engers D, Leach K, Schields P, Jang Y (2010) Effect of water vapor sorption on local structure of poly(vinylpyrrolidone). J Pharm Sci 99:3815–3825
38.
Busselez R, Arbe A, Cerveny S, Capponi S, Colmenero J, Frick B (2012) Component dynamics in polyvinylpyrrolidone concentrated aqueous solutions. J Chem Phys 137:084902
39.
Naohara R, Narita K, Ikeda-Fukazawa T (2017) Change in hydrogen bonding structures of a hydrogel with dehydration. Chem Phys Lett 670:84–88
40.
Omidian H, Park K (2010) Introduction to hydrogels. In: Ottenbrite RM (ed) Biomedical applications of hydrogels handbook. Springer, London, pp 1–16
41.
42.
Hammouda B, Ho DL, Kline S (2004) Insight into clustering in poly (ethylene oxide) solutions. Macromolecules 37:6932–6937
43.
Teodorescu M, Morariu S, Bercea M, Sacarescu L (2016) Viscoelastic and structural properties of poly(vinyl alcohol)/poly(vinylpyrrolidone) hydrogels. RSC Adv 6:39718–39727
44.
Gennes PG (1979) Scaling Concepts in Polymer Physics. Cornell University Press, Ithaca
45.
Campanella A, Holderer O, Raftopoulos KN, Papadakis CM, Staropoli MP, Appavou MS, Muller-Buschbaum P, Frielinghaus H (2016) Multi-stage freezing of HEUR polymer networks with magnetite nanoparticles. Soft Matter 12:3214–3225
46.
Berke B, Czakkel O, Porcar L, Geissler E, Laszlo K (2016) Static and dynamic behaviour of responsive graphene oxide–poly(N-isopropyl acrylamide) composite gels. Soft Matter 12:7166–7173
47.
Hellweg T, Kratz K, Pouget S, Eimer W (2002) Internal dynamics in colloidal pNIPAM microgel particles immobilised in a mesoscopic crystal. Coll Surf A 202:223–232
48.
Robinson GW, Zhu SB, Singh S, Evans MW (1996) Water in biology, chemistry, and physics: experimental overviews and computational methodologies. World Scientific, Singapore
49.
Adnadjevic B, Jovanovic J (2008) Novel approach in investigation of the poly(acrylic acid) hydrogel swelling kinetics in water. J Appl Polym Sci 107:3579–3587
50.
Datsenko B, Biryukova SV, Tamm TI (1989) Methodical recommendations for experimental (preclinical) study of drugs for topical treatment of purulent wounds. USSR, Moscow
Metadata
Title
Synthesis and physico-chemical properties of poly(N-vinyl pyrrolidone)-based hydrogels with titania nanoparticles
Authors
Olesya Timaeva
Igor Pashkin
Sergey Mulakov
Galina Kuzmicheva
Petr Konarev
Raisa Terekhova
Natalia Sadovskaya
Orsolya Czakkel
Sylvain Prevost
Publication date
22-11-2019
Publisher
Springer US
Published in
Journal of Materials Science / Issue 7/2020
Print ISSN: 0022-2461
Electronic ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-019-04230-z

Other articles of this Issue 7/2020

Journal of Materials Science 7/2020 Go to the issue

Chemical routes to materials

Synthesis of single-layer graphene film by chemical vapor deposition with molten gallium catalyst on silicon dioxide

Electronic materials

Effects of Pb doping on the electrical transport performance of Cu1.98Se

Energy materials

Single-crystal LiNi0.5Co0.2Mn0.3O2: a high thermal and cycling stable cathodes for lithium-ion batteries

Materials for life sciences

The suitability of Synbone® as a tissue analogue in ballistic impacts

Energy materials

Two-dimensional layered materials InSe nanoflakes/carbon nanotubes composite for flexible all-solid-state supercapacitors

Energy materials

High perovskite-to-manganese energy transfer efficiency in single-component white-emitting Mn-doped halide perovskite quantum dots

Premium Partners

    Image Credits