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Quality of Life Research
Published in: Quality of Life Research 12/2020

01-07-2020

The influence of trait mindfulness on depression in multiple sclerosis: potential implications for treatment

Authors: Jennifer R. Miller, Caroline Altaras, Nicholas A. Vissicchio, Vance Zemon, Jeffrey G. Portnoy, Elizabeth S. Gromisch, Jessica Sloan, Tuula Tyry, Frederick W. Foley

Published in: Quality of Life Research | Issue 12/2020

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Abstract

Purpose

This study seeks to add to existing literature on depression and illness intrusiveness in chronic disorders by examining, (1) how the perceived intrusiveness of multiple sclerosis (MS) leads to depression, (2) and the mediating role trait mindfulness plays in this relationship

Methods

Participants (N = 755) were persons with MS (PwMS) recruited through the North American Research Committee on MS (NARCOMS) registry (a larger study). Participants completed the Illness Intrusiveness Ratings Scale, the Hospital Anxiety and Depression Scale and the Mindful Attention Awareness Scale. A mediation model assessed if trait mindfulness mediates the relationship between illness intrusiveness and depression

Results

Illness intrusiveness predicted trait mindfulness (a =  − 4.54; p < .001), trait mindfulness predicted depression (b =  − .04; p < .001); there was a direct effect of illness intrusiveness on depression (c’ = 2.53; p < .001) and an indirect effect on depression (ab = .17, 95% BCa CI [.10, .25]) when trait mindfulness was in the model, which represented a medium size effect, R2med = .10 [95% CI .07, .14]

Conclusion

Trait mindfulness mediates the relationship between illness intrusiveness and depression in PwMS. Providers could provide psychoeducation on the benefits of mindfulness and mindfulness-based interventions.
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Metadata
Title
The influence of trait mindfulness on depression in multiple sclerosis: potential implications for treatment
Authors
Jennifer R. Miller
Caroline Altaras
Nicholas A. Vissicchio
Vance Zemon
Jeffrey G. Portnoy
Elizabeth S. Gromisch
Jessica Sloan
Tuula Tyry
Frederick W. Foley
Publication date
01-07-2020
Publisher
Springer International Publishing
Published in
Quality of Life Research / Issue 12/2020
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02567-6

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