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2018 | OriginalPaper | Chapter

Tumor Delineation for Brain Radiosurgery by a ConvNet and Non-uniform Patch Generation

Authors : Egor Krivov, Valery Kostjuchenko, Alexandra Dalechina, Boris Shirokikh, Gleb Makarchuk, Alexander Denisenko, Andrey Golanov, Mikhail Belyaev

Published in: Patch-Based Techniques in Medical Imaging

Publisher: Springer International Publishing

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Abstract

Deep learning methods are actively used for brain lesion segmentation. One of the most popular models is DeepMedic, which was developed for segmentation of relatively large lesions like glioma and ischemic stroke. In our work, we consider segmentation of brain tumors appropriate to stereotactic radiosurgery which limits typical lesion sizes. These differences in target volumes lead to a large number of false negatives (especially for small lesions) as well as to an increased number of false positives for DeepMedic. We propose a new patch-sampling procedure to increase network performance for small lesions. We used a 6-year dataset from a stereotactic radiosurgery center. To evaluate our approach, we conducted experiments with the three most frequent brain tumors: metastasis, meningioma, schwannoma. In addition to cross-validation, we estimated quality on a hold-out test set which was collected several years later than the train one. The experimental results show solid improvements in both cases.

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Metadata
Title
Tumor Delineation for Brain Radiosurgery by a ConvNet and Non-uniform Patch Generation
Authors
Egor Krivov
Valery Kostjuchenko
Alexandra Dalechina
Boris Shirokikh
Gleb Makarchuk
Alexander Denisenko
Andrey Golanov
Mikhail Belyaev
Copyright Year
2018
DOI
https://doi.org/10.1007/978-3-030-00500-9_14

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