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2018 | OriginalPaper | Chapter

Usability Evaluation of Origin of Replication Finding Tools

Authors : Isra Al-Turaiki, Maryam Aloumi, Nour Aloumi, Noorah Almanyi, Khulood Alghamdi, Sarah Almuqhim

Published in: Human-Computer Interaction. Interaction in Context

Publisher: Springer International Publishing

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Abstract

Nowadays, there is a significant increase in the number of Bioinformatics tools and databases. Researchers from various interdisciplinary fields need to use these tools. Usability is an important quality of software in general, and bioinformatics tools in particular. Improving the usability of bioinformatics tools allows users to use the tool to its fullest potential. In this paper, we evaluate the usability of two online bioinformatics tools Ori-Finder 1 and Ori-Finder 2 in terms of efficiency, effectiveness, and satisfaction. The evaluation focuses on investigating how easily and successfully can users use Ori-Finder1 and Ori-Finder 2 to find the origin of replication in Bacterial and Archaeal genomes. To the best of our knowledge, the usability of these two tools has not been studied before. Twelve participants were recruited from four user groups. The average tasks completion times were compared. Many usability issues were identified by users of bioinformatics tools. Based on our results, we list recommendations for better design of bioinformatics tools.

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Literature
1.
2.
Al-Ageel, N., Al-Wabil, A., Badr, G., AlOmar, N.: Human factors in the design and evaluation of bioinformatics tools. Procedia Manuf. 3, 2003–2010 (2015)CrossRef
3.
Altschul, S.F., Gish, W., Miller, W., Myers, E.W., Lipman, D.J.: Basic local alignment search tool. J. Mol. Biol. 215(3), 403–410 (1990)CrossRef
4.
Bailey, T.L., Boden, M., Buske, F.A., Frith, M., Grant, C.E., Clementi, L., Ren, J., Li, W.W., Noble, W.S.: MEME Suite: tools for motif discovery and searching. Nucleic Acids Res. 37(suppl–2), W202–W208 (2009)CrossRef
5.
Bolchini, D., Finkelstein, A., Perrone, V., Nagl, S.: Better bioinformatics through usability analysis. Bioinformatics 25(3), 406–412 (2009)CrossRef
6.
7.
Chang, T.H., Huang, H.D., Chuang, T.N., Shien, D.M., Horng, J.T.: RNAMST: efficient and flexible approach for identifying RNA structural homologs. Nucleic Acids Res. 34(Suppl–2), W423–W428 (2006)CrossRef
8.
Delcher, A.L., Bratke, K.A., Powers, E.C., Salzberg, S.L.: Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics 23(6), 673–679 (2007)CrossRef
9.
Gao, F., Zhang, C.T.: Ori-Finder: a web-based system for finding oriC s in unannotated bacterial genomes. BMC Bioinformatics 9, 79 (2008)CrossRef
10.
Grant, C.E., Bailey, T.L., Noble, W.S.: FIMO: scanning for occurrences of a given motif. Bioinformatics 27(7), 1017–1018 (2011)CrossRef
11.
Guo, F.B., Ou, H.Y., Zhang, C.T.: ZCURVE: a new system for recognizing protein-coding genes in bacterial and archaeal genomes. Nucleic Acids Res. 31(6), 1780–1789 (2003)CrossRef
12.
Kurtz, S., Choudhuri, J.V., Ohlebusch, E., Schleiermacher, C., Stoye, J., Giegerich, R.: REPuter: the manifold applications of repeat analysis on a genomic scale. Nucleic Acids Res. 29(22), 4633–4642 (2001)CrossRef
13.
Leonard, A.C., Mechali, M.: DNA replication origins. Cold Spring Harb. Perspect. Biol. 5(10), a010116 (2013)CrossRef
14.
Luo, H., Zhang, C.T., Gao, F.: Ori-Finder 2, an integrated tool to predict replication origins in the archaeal genomes. Front. Microbiol. 5, 482 (2014)
15.
16.
Mullany, L.E., Wolff, R.K., Slattery, M.L.: Effectiveness and usability of bioinformatics tools to analyze pathways associated with miRNA expression. Cancer Inform. 14, 121–130 (2015)CrossRef
17.
Rabani, M., Kertesz, M., Segal, E.: Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes. Proc. Natl. Acad. Sci. 105(39), 14885–14890 (2008)CrossRef
Metadata
Title
Usability Evaluation of Origin of Replication Finding Tools
Authors
Isra Al-Turaiki
Maryam Aloumi
Nour Aloumi
Noorah Almanyi
Khulood Alghamdi
Sarah Almuqhim
Copyright Year
2018
Book
Human-Computer Interaction. Interaction in Context

Print ISBN: 978-3-319-91243-1

Electronic ISBN: 978-3-319-91244-8

Copyright Year: 2018

DOI
https://doi.org/10.1007/978-3-319-91244-8_1