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Journal of Nanoparticle Research

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01-06-2015 | Review

ZnO and TiO₂ nanoparticles as novel antimicrobial agents for oral hygiene: a review

Authors: Shams Tabrez Khan, Abdulaziz A. Al-Khedhairy, Javed Musarrat

Published in: Journal of Nanoparticle Research | Issue 6/2015

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Abstract

Oral cavity is inhabited by more than 25,000 different bacterial phylotypes; some of them cause systemic infections in addition to dental and periodontal diseases. Emergence of multiple antibiotic resistance among these bacteria necessitates the development of alternative antimicrobial agents that are safe, stable, and relatively economic. This review focuses on the significance of metal oxide nanoparticles, especially zinc oxide and titanium dioxide nanoparticles as supplementary antimicrobials for controlling oral infections and biofilm formation. Indeed, the ZnO NPs and TiO₂ NPs have exhibited significant antimicrobial activity against oral bacteria at concentrations which is not toxic in in vivo toxicity assays. These nanoparticles are being produced at an industrial scale for use in a variety of commercial products including food products. Thus, the application of ZnO and TiO₂ NPs as nanoantibiotics for the development of mouthwashes, dental pastes, and other oral hygiene materials is envisaged. It is also suggested that these NPs could serve as healthier, innocuous, and effective alternative for controlling both the dental biofilms and oral planktonic bacteria with lesser side effects and antibiotic resistance.

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Title: ZnO and TiO2 nanoparticles as novel antimicrobial agents for oral hygiene: a review
Authors: Shams Tabrez Khan
Abdulaziz A. Al-Khedhairy
Javed Musarrat
Publication date: 01-06-2015
Publisher: Springer Netherlands
Published in: Journal of Nanoparticle Research / Issue 6/2015
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-015-3074-6

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