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Published in: Microsystem Technologies 9/2017

06-05-2016 | Technical Paper

A stack bonded thermo-pneumatic micro-pump utilizing polyimide based actuator membrane for biomedical applications

Authors: Norihan Abdul Hamid, Burhanuddin Yeop Majlis, Jumril Yunas, A. R. Syafeeza, Yan Chiew Wong, Mazree Ibrahim

Published in: Microsystem Technologies | Issue 9/2017

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Abstract

This paper presents a simple and low-cost fabrication method of thermo pneumatic micropump with very thin polyimide (Pi) membrane. The measurement and functional testing of the whole micropump system is investigated as well. The thermo-pneumatic micropump consists of three main components, such as micro heater, thin film membrane with thermal cavity and planar valve with diffuser nozzle. Three different processes were used to fabricate the micropump due to different material used in each component. The thin polyimide membrane acts as an actuator and actuated by thermal expansion volume in thermal chamber. The diameter and the thickness of the actuator diaphragm are 2 mm2 and 3.5 µm, respectively. The meniscus motion in the outlet tube is observed with a microscope image video and the flow rate of the micropump is calculated through the frame analysis of the recorded video data. The flow rate range of the micropump is about 770 pL to 12.5 nL at approximately 33.5–63.5 °C, when the input voltage of 2–12 V applied to the micro heater. This flow rate range is suitable to be used with artificial kidney function, nano pipet and other biomedical application.

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Literature
go back to reference Abhari F, Jaafar H, Yunus NA (2014) A comprehensive study of micropumps technologies. Int J Electrochem Sci 7:9765–9780 Abhari F, Jaafar H, Yunus NA (2014) A comprehensive study of micropumps technologies. Int J Electrochem Sci 7:9765–9780
go back to reference Amirouche F, Zhou Y, Johnson T (2009) Current micropump technologies and their biomedical applications. Microsyst Technol 15(5):647–666CrossRef Amirouche F, Zhou Y, Johnson T (2009) Current micropump technologies and their biomedical applications. Microsyst Technol 15(5):647–666CrossRef
go back to reference Birch TS, Shearwood JC, Harradine M, Stevens (1996) Applications of polyimide membranes to MEMS technology. Microelectron Eng 30:547–550 Birch TS, Shearwood JC, Harradine M, Stevens (1996) Applications of polyimide membranes to MEMS technology. Microelectron Eng 30:547–550
go back to reference Cantwell ML, Amirouche F, Citerin J (2011) Low-cost high performance disposable micropump for fluidic delivery applications. Sensors Actuators A Phys 168(1):187–194CrossRef Cantwell ML, Amirouche F, Citerin J (2011) Low-cost high performance disposable micropump for fluidic delivery applications. Sensors Actuators A Phys 168(1):187–194CrossRef
go back to reference Dario P, Carrozza MC, Benvenuto A, Menciassi A (2000) Micro-systems in biomedical applications. J Micromech Microeng 10(2):235–244CrossRef Dario P, Carrozza MC, Benvenuto A, Menciassi A (2000) Micro-systems in biomedical applications. J Micromech Microeng 10(2):235–244CrossRef
go back to reference Hamid NA, Yunas J, Bahadorimehr AR, Majlis BY (2011) Design consideration of membrane structure for thermal actuated micropump. Adv Mater Res 254:42–45CrossRef Hamid NA, Yunas J, Bahadorimehr AR, Majlis BY (2011) Design consideration of membrane structure for thermal actuated micropump. Adv Mater Res 254:42–45CrossRef
go back to reference Hamid NA, Yunas J, Majlis BY (2012) The effect of isopropyl alcohol on anisotropic etched silicon for the fabrication of microheater chamber. In: IEEE Conf. On Semiconductor Electronic., pp 210–213 Hamid NA, Yunas J, Majlis BY (2012) The effect of isopropyl alcohol on anisotropic etched silicon for the fabrication of microheater chamber. In: IEEE Conf. On Semiconductor Electronic., pp 210–213
go back to reference Nguyen CH, Aici G, Wallace G (2014) An advanced mathematical model and its experimental verification fro trilayer conjugated polymer actuator. In: IEEE ASME Trans. on Mechatronic, pp 1279–1288 Nguyen CH, Aici G, Wallace G (2014) An advanced mathematical model and its experimental verification fro trilayer conjugated polymer actuator. In: IEEE ASME Trans. on Mechatronic, pp 1279–1288
go back to reference Nisar A, Afzulpurkar N, Mahaisavariya B, Tuantranont A (2008a) MEMS-based micropumps in drug delivery and biomedical applications. Sensors Actuators B Chem 130(2):917–942CrossRef Nisar A, Afzulpurkar N, Mahaisavariya B, Tuantranont A (2008a) MEMS-based micropumps in drug delivery and biomedical applications. Sensors Actuators B Chem 130(2):917–942CrossRef
go back to reference Nisar AA, Mahaisavariya B, Tuantranont A (2008b) MEMS based micropumps in drug delivery and biomedical application. Sensor Actuator B Chem 130(12):917–942CrossRef Nisar AA, Mahaisavariya B, Tuantranont A (2008b) MEMS based micropumps in drug delivery and biomedical application. Sensor Actuator B Chem 130(12):917–942CrossRef
go back to reference Podder PK, Samajdar DP, Mallick D, Bhattacharyya A (2012) Design and simulation of micro-pump, micro-valve and micro-needle for biomedical applications. 5th Int Conf Comput Devices Commun 3:1–4 Podder PK, Samajdar DP, Mallick D, Bhattacharyya A (2012) Design and simulation of micro-pump, micro-valve and micro-needle for biomedical applications. 5th Int Conf Comput Devices Commun 3:1–4
go back to reference Said MM, Yunas J, Ekapawinto R, Majlis BY, Bais B (2014) Synthesization of nickel nanoparticles embedded in SU8 polymer for electromagnetic actuator membrane. In: IEEE Conf. of Semictor Electronic (ICSE), pp 213–216 Said MM, Yunas J, Ekapawinto R, Majlis BY, Bais B (2014) Synthesization of nickel nanoparticles embedded in SU8 polymer for electromagnetic actuator membrane. In: IEEE Conf. of Semictor Electronic (ICSE), pp 213–216
go back to reference Setat F, Ortega I, McKean R, Deshpande P, Ramacandran C, Hill CJ, Tzoko SB, Claeyssens F, Sangwan VS, Ryan AJ, MacNeil S (2014) An off the shelf synthetic membrane to simply regeneration od damaged cornea. In: Middle East Conference on Bio Medical Engineering (MECBME), pp 59–62 Setat F, Ortega I, McKean R, Deshpande P, Ramacandran C, Hill CJ, Tzoko SB, Claeyssens F, Sangwan VS, Ryan AJ, MacNeil S (2014) An off the shelf synthetic membrane to simply regeneration od damaged cornea. In: Middle East Conference on Bio Medical Engineering (MECBME), pp 59–62
go back to reference Shawgo RS, Grayson ACR, Li Y, Cima MJ (2002) BioMEMS for drug delivery. Solid State Mater Sci 6:329–334CrossRef Shawgo RS, Grayson ACR, Li Y, Cima MJ (2002) BioMEMS for drug delivery. Solid State Mater Sci 6:329–334CrossRef
go back to reference Tsai NC, Sue CY (2007) Review of MEMS based drug delivery and dosring system. Sensor Actuator A Phys 134(2):555–564CrossRef Tsai NC, Sue CY (2007) Review of MEMS based drug delivery and dosring system. Sensor Actuator A Phys 134(2):555–564CrossRef
go back to reference Vereschagina E, Bourle K, Meehan L, Dixit C, Gille DM, Ducree J (2013) Multi material paper device for low cost biomedical diagnostics. In: IEEE 20th Int. Conf. of MEMS, pp 1049–1052 Vereschagina E, Bourle K, Meehan L, Dixit C, Gille DM, Ducree J (2013) Multi material paper device for low cost biomedical diagnostics. In: IEEE 20th Int. Conf. of MEMS, pp 1049–1052
go back to reference Yoo JC, Kang CJ, Kim YS, La GS (2008) Microfabricated polydimethylsiloxane microfluidic system including micropump and microvalve for integrated biosensor. Curr Appl Phys 8:692–695CrossRef Yoo JC, Kang CJ, Kim YS, La GS (2008) Microfabricated polydimethylsiloxane microfluidic system including micropump and microvalve for integrated biosensor. Curr Appl Phys 8:692–695CrossRef
go back to reference Yunas J, Johari J, Bahadorimehr AR, Gebeshuber IC, Majlis BY (2011) Investigation of simple process technology for the fabrication of valveless micropumps. Adv Mater Res 254:211–214CrossRef Yunas J, Johari J, Bahadorimehr AR, Gebeshuber IC, Majlis BY (2011) Investigation of simple process technology for the fabrication of valveless micropumps. Adv Mater Res 254:211–214CrossRef
Metadata
Title
A stack bonded thermo-pneumatic micro-pump utilizing polyimide based actuator membrane for biomedical applications
Authors
Norihan Abdul Hamid
Burhanuddin Yeop Majlis
Jumril Yunas
A. R. Syafeeza
Yan Chiew Wong
Mazree Ibrahim
Publication date
06-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Microsystem Technologies / Issue 9/2017
Print ISSN: 0946-7076
Electronic ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-016-2951-y

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