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2019 | OriginalPaper | Chapter

Activation of Lipase-Catalyzed Reactions Using Ionic Liquids for Organic Synthesis

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Abstract

Abstract

The use of ionic liquids to replace organic or aqueous solvents in biocatalysis processes has recently received great attention, and much progress has been made in this area; the lipase-catalyzed reactions are the most successful. Recent developments in the application of ionic liquids as solvents in lipase-catalyzed reactions for organic synthesis are reviewed, focusing on the ionic liquid mediated activation method of lipase-catalyzed reactions.

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Glossary
[C2mim]+
1-Ethyl-3-methylimidazolium
[C4mim]+
1-Butyl-3-methylimidazolium
[C4dmim]+
1-Butyl-2,3-dimethylimidazolium
[HOPmim]+
1-Methyl-3-(3-hydroxy)propylimidazolium
[3-Ph-C3mim]+
1-Methyl-3(3-phenylpropyl)imidazolium
[C16tam]+
N-Cetyl-N,N,N-trimethylammonium
[Me(OCH2CH2)3-Et-Pip]+
Ethyl (2-(2-methoxyethoxy)ethoxy)ethylpiperidin-1-ium
[Me(OCH2CH2)3-Et3N]+
Triethyl (2-(2-methoxyethoxy)ethoxy)ethylammonium
[Me(OCH2CH2)3eim]+
1-Ethyl-3-(2-(2-methoxyethoxy)ethoxy)ethylimidazolium
L-Pro-Me
(S)-1-Butyl-2-methyl-3-(pyrrolidin-2-ylmethyl)-1H-imidazol-3-ium
L-Pro-H
(S)-1-Butyl-3-(pyrrolidin-2-ylmethyl)-1H-imidazol-3-ium
D-Pro-H
(R)-1-Butyl-3-(pyrrolidin-2-ylmethyl)-1H-imidazol-3-ium
D-Pro-Me
(R)-1-Butyl-2-methyl-3-(pyrrolidin-2-ylmethyl)-1H-imidazol-3-ium
[N221MEM]+
N,N-Diethyl-N-methyl-N-(2-methoxyethoxymethyl)ammonium
[N2222]+
N,N,N-Tetraethylammonium
[P444ME]+
Tributyl(2-methoxyethyl)phosphonium
[P444MEM]+
Tributyl(2-methoxyethoxyethyl)phosphonium
[TAC1]+
Tris(diethylamino)cyclopropenium
[TEA]+
N,N,N,N-Tetraethylammonium
[PP22]+
N,N-Diethylpiperidinium
[Tz1]+
1-Butyl-3-methyltriazolium
[Tz2]+
1-Benzyl-3-methyltriazolium
[Tz3]+
1-Butyl-3-methyl-5-(hydroxymethyl)triazolium
[OAc]−
Acetate
[BF4]−
Tetrafluoroborate
[NO3]–
Nitrate
[OTf]−
Trifluoromethanesulfonate
[Tf2N]−
Bis(trifluoromethylsulfonyl)amide. [Tf2N] is widely known as “bis(trifluoromethylsulfonyl)imide.” However, “imide” means “an amido compound which is connected with two carbonyl groups,” so [Tf2N] should be labelled as “bis(trifluoromethylsulfonyl)amide” according to the IUPAC rule
ISCB1
Potassium 3,5-bis(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)benzoate (ISCB1)
IL1
1-Butyl-2,3-dimethylimidazolium 3,6,9,12,15,18,21,24,27,30-decaoxacetyltriacontyl sulfate (cetyl-PEG10 sulfate)
DES
Deep eutectic solvent
AMMOENG 102™
See Fig. 22
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Metadata
Title
Activation of Lipase-Catalyzed Reactions Using Ionic Liquids for Organic Synthesis
Author
Toshiyuki Itoh
Copyright Year
2019
DOI
https://doi.org/10.1007/10_2018_62

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