An Adaptive Level Set Method for Medical Image Segmentation

An efficient adaptive multigrid level set method for front propagation purposes in three dimensional medical image segmentation is presented. It is able to deal with non sharp segment boundaries. A flexible, interactive modulation of the front speed depending on various boundary and regularization criteria ensure this goal. Efficiency is due to a graded underlying mesh implicitly defined via error or feature indicators. A suitable saturation condition ensures an important regularity condition on the resulting adaptive grid. As a casy study the segmentation of glioma is considered. The clinician interactively selects a few parameters describing the speed function and a few seed points. The automatic process of front propagation then generates a family of segments corresponding to the evolution of the front in time, from which the clinician finally selects an appropriate segment covered by the gliom. Thus, the overall glioma segmentation turns into an efficient, nearly real time process with intuitive and usefully restricted user interaction.