Skip to main content
Top

2017 | OriginalPaper | Chapter

An Ions-Medicated Single Molecular Multi-functional DNA Cascade Logic Circuit and Signal Amplifier Model

Authors : Bingjie Guo, Xiangxiang Chen, Tao Wu, Yafei Dong

Published in: Bio-inspired Computing: Theories and Applications

Publisher: Springer Singapore

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

In this paper, a single molecular multi-functional DNA cascade logic circuit and signal amplifier model was demonstrated by two single molecular multi-functional ions DNA probe(SMIP) to detect environment mercury and silver ion pollution, these two SMIP random coil structures turned into different hairpin-like structures with T-Hg\(^{2+}\)-T or C-Ag\(^{+}\)-C via inputting mercury and silver ions, then, use the SMIP structure “OR” and “AND” logic gate and unimolecular mulfunctional DNA logic amplifier model (UMDA). Finally, we proved the feasibility of our model by PAGE and fluorescence alteration.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literature
1.
go back to reference Chansuvarn, W., Tuntulani, T., Imyim, A.: Colorimetric detection of mercury(II) based on gold nanoparticles, fluorescent gold nanoclusters and other gold-based nanomaterials. Trac-Trend. Anal. Chem. 65, 83–96 (2014)CrossRef Chansuvarn, W., Tuntulani, T., Imyim, A.: Colorimetric detection of mercury(II) based on gold nanoparticles, fluorescent gold nanoclusters and other gold-based nanomaterials. Trac-Trend. Anal. Chem. 65, 83–96 (2014)CrossRef
2.
go back to reference Lee, J.S., Han, M.S., Mirkin, C.A.: Colorimetric detection of mercuric ion (Hg 2+) in aqueous media using DNA-functionalized gold nanoparticles. Angew. Chem. 46(22), 4093 (2007)CrossRef Lee, J.S., Han, M.S., Mirkin, C.A.: Colorimetric detection of mercuric ion (Hg 2+) in aqueous media using DNA-functionalized gold nanoparticles. Angew. Chem. 46(22), 4093 (2007)CrossRef
3.
go back to reference Wang, S., Xu, H., Yang, Q., et al.: A triphenylamine-based colorimetric and turn-on fluorescent probe for detection of cyanide anions in live cells. RSC Adv. 5(59), 47990–47996 (2015)CrossRef Wang, S., Xu, H., Yang, Q., et al.: A triphenylamine-based colorimetric and turn-on fluorescent probe for detection of cyanide anions in live cells. RSC Adv. 5(59), 47990–47996 (2015)CrossRef
4.
go back to reference Li, L., Li, B., Di, C., et al.: Visual detection of melamine in raw milk using gold nanoparticles as colorimetric probe. Food Chem. 122(3), 895–900 (2010)CrossRef Li, L., Li, B., Di, C., et al.: Visual detection of melamine in raw milk using gold nanoparticles as colorimetric probe. Food Chem. 122(3), 895–900 (2010)CrossRef
5.
go back to reference Li, L., Li, B., Qi, Y., et al.: Label-free aptamer-based colorimetric detection of mercury ions in aqueous media using unmodified gold nanoparticles as colorimetric probe. Anal. Bioanal. Chem. 393(8), 2051–7 (2009)CrossRef Li, L., Li, B., Qi, Y., et al.: Label-free aptamer-based colorimetric detection of mercury ions in aqueous media using unmodified gold nanoparticles as colorimetric probe. Anal. Bioanal. Chem. 393(8), 2051–7 (2009)CrossRef
6.
go back to reference Miyake, Y., Togashi, H., Tashiro, M., et al.: Mercury II-mediated formation of thymine-Hg II-thymine base pairs in DNA duplexes. J. Am. Chem. Soc. 128, 2172–2173 (2006)CrossRef Miyake, Y., Togashi, H., Tashiro, M., et al.: Mercury II-mediated formation of thymine-Hg II-thymine base pairs in DNA duplexes. J. Am. Chem. Soc. 128, 2172–2173 (2006)CrossRef
7.
go back to reference Zuo, X., Zhang, H., Zhu, Q., et al.: A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg(2+) and Ag(+). Biosens. Bioelectron. 85, 464 (2016)CrossRef Zuo, X., Zhang, H., Zhu, Q., et al.: A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg(2+) and Ag(+). Biosens. Bioelectron. 85, 464 (2016)CrossRef
8.
go back to reference Gómez-Ariza, J.L., Lorenzo, F., Garcia-Barrera, T.: Comparative study of atomic fluorescence spectroscopy and inductively coupled plasma mass spectrometry for mercury and arsenic multispeciation. Anal. Bioanal. Chem. 382(2), 485–492 (2005)CrossRef Gómez-Ariza, J.L., Lorenzo, F., Garcia-Barrera, T.: Comparative study of atomic fluorescence spectroscopy and inductively coupled plasma mass spectrometry for mercury and arsenic multispeciation. Anal. Bioanal. Chem. 382(2), 485–492 (2005)CrossRef
9.
go back to reference Fong, B.M.W., Siu, T.S., Lee, J.S.K., et al.: Determination of mercury in whole blood and urine by inductively coupled plasma mass spectrometry. J. Anal. Toxicol. 31(5), 281 (2017)CrossRef Fong, B.M.W., Siu, T.S., Lee, J.S.K., et al.: Determination of mercury in whole blood and urine by inductively coupled plasma mass spectrometry. J. Anal. Toxicol. 31(5), 281 (2017)CrossRef
10.
go back to reference Qing, Z., He, X.: Colorimetric multiplexed analysis of mercury and silver ions by using a unimolecular DNA probe and unmodified gold nanoparticles. Anal. Methods 4(10), 3320–3325 (2012)CrossRef Qing, Z., He, X.: Colorimetric multiplexed analysis of mercury and silver ions by using a unimolecular DNA probe and unmodified gold nanoparticles. Anal. Methods 4(10), 3320–3325 (2012)CrossRef
11.
go back to reference Deng, W., Tan, Y., Li, Y., et al.: Square wave voltammetric determination of Hg(II) using thiol functionalized chitosan-multiwalled carbon nanotubes nanocomposite film electrode. Microchim. Acta 169(3–4), 367–373 (2010)CrossRef Deng, W., Tan, Y., Li, Y., et al.: Square wave voltammetric determination of Hg(II) using thiol functionalized chitosan-multiwalled carbon nanotubes nanocomposite film electrode. Microchim. Acta 169(3–4), 367–373 (2010)CrossRef
12.
go back to reference Zhao, J., Zhu, L., Guo, C., et al.: A new electrochemical method for the detection of cancer cells based on small molecule-linked DNA. Biosens. Bioelectron. 49(11), 329–333 (2013)CrossRef Zhao, J., Zhu, L., Guo, C., et al.: A new electrochemical method for the detection of cancer cells based on small molecule-linked DNA. Biosens. Bioelectron. 49(11), 329–333 (2013)CrossRef
13.
go back to reference Wang, F., Liu, X., Willner, I.: DNA Switches: from Principles to Applications. Angew. Chem. Int. Edit. 54(4), 1098–129 (2015)CrossRef Wang, F., Liu, X., Willner, I.: DNA Switches: from Principles to Applications. Angew. Chem. Int. Edit. 54(4), 1098–129 (2015)CrossRef
14.
go back to reference Miyake, Y., Togashi, H., Tashiro, M., et al.: MercuryII-mediated formation of Thymine-HgII-Thymine base pairs in DNA duplexes. J. Am. Chem. Soc. 128(7), 2172–3 (2006)CrossRef Miyake, Y., Togashi, H., Tashiro, M., et al.: MercuryII-mediated formation of Thymine-HgII-Thymine base pairs in DNA duplexes. J. Am. Chem. Soc. 128(7), 2172–3 (2006)CrossRef
15.
go back to reference Tanaka, Y., Oda, S., Yamaguchi, H., et al.: 15N–15N J-coupling across Hg(II): direct observation of Hg(II)-mediated T-T base pairs in a DNA Duplex. J. Am. Chem. Soc. 129(2), 244–5 (2007)CrossRef Tanaka, Y., Oda, S., Yamaguchi, H., et al.: 15N–15N J-coupling across Hg(II): direct observation of Hg(II)-mediated T-T base pairs in a DNA Duplex. J. Am. Chem. Soc. 129(2), 244–5 (2007)CrossRef
16.
go back to reference Ono, A., Cao, S., Togashi, H., et al.: Specific interactions between silver(I) ions and cytosine-cytosine pairs in DNA duplexes. Chem. Commun. 39(39), 4825 (2008)CrossRef Ono, A., Cao, S., Togashi, H., et al.: Specific interactions between silver(I) ions and cytosine-cytosine pairs in DNA duplexes. Chem. Commun. 39(39), 4825 (2008)CrossRef
17.
go back to reference Feng, W., Xue, X., Liu, X.: One-step, room-temperature, colorimetric detection of mercury (Hg(2+)) using DNA/nanoparticle conjugates. J. Am. Chem. Soc. 130(11), 3244–3245 (2008)CrossRef Feng, W., Xue, X., Liu, X.: One-step, room-temperature, colorimetric detection of mercury (Hg(2+)) using DNA/nanoparticle conjugates. J. Am. Chem. Soc. 130(11), 3244–3245 (2008)CrossRef
18.
go back to reference He, X., Qing, Z., Wang, K., et al.: Engineering a unimolecular multifunctional DNA probe for analysis of Hg2+ and Ag+. Anal. Methods. 4(2), 345–347 (2012)CrossRef He, X., Qing, Z., Wang, K., et al.: Engineering a unimolecular multifunctional DNA probe for analysis of Hg2+ and Ag+. Anal. Methods. 4(2), 345–347 (2012)CrossRef
19.
go back to reference Yun, L., Yang, L., Mao, X., et al.: Electrochemical detection of glutathione based on Hg 2+ -mediated strand displacement reaction strategy. Biosens. Bioelectron. 85, 664–668 (2016)CrossRef Yun, L., Yang, L., Mao, X., et al.: Electrochemical detection of glutathione based on Hg 2+ -mediated strand displacement reaction strategy. Biosens. Bioelectron. 85, 664–668 (2016)CrossRef
20.
go back to reference Farhadtoosky, S., Jahanian, A.: Customized placement algorithm of nanoscale DNA logic circuits. J. Circuit. Syst. Comp. 26(10), 1750150 (2017)CrossRef Farhadtoosky, S., Jahanian, A.: Customized placement algorithm of nanoscale DNA logic circuits. J. Circuit. Syst. Comp. 26(10), 1750150 (2017)CrossRef
21.
go back to reference Yang, J., Dong, C., Dong, Y., et al.: Logic nanoparticle beacon triggered by the binding-induced effect of multiple inputs. Acs Appl. Mater. Inter. 6(16), 14486–14492 (2014)CrossRef Yang, J., Dong, C., Dong, Y., et al.: Logic nanoparticle beacon triggered by the binding-induced effect of multiple inputs. Acs Appl. Mater. Inter. 6(16), 14486–14492 (2014)CrossRef
Metadata
Title
An Ions-Medicated Single Molecular Multi-functional DNA Cascade Logic Circuit and Signal Amplifier Model
Authors
Bingjie Guo
Xiangxiang Chen
Tao Wu
Yafei Dong
Copyright Year
2017
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-7179-9_33

Premium Partner