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Nanomaterial-Modified Capacitive Field-Effect Biosensors Read chapter Read first chapter

2018 | OriginalPaper | Chapter

(Bio-)chemical Sensing and Imaging by LAPS and SPIM

Authors : Tatsuo Yoshinobu, Steffi Krause, Ko-ichiro Miyamoto, Carl Frederik Werner, Arshak Poghossian, Torsten Wagner, Michael J. Schöning

Published in: Label-Free Biosensing

Publisher: Springer International Publishing

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Abstract

The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.

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Metadata
Title
(Bio-)chemical Sensing and Imaging by LAPS and SPIM
Authors
Tatsuo Yoshinobu
Steffi Krause
Ko-ichiro Miyamoto
Carl Frederik Werner
Arshak Poghossian
Torsten Wagner
Michael J. Schöning
Copyright Year
2018
Book
Label-Free Biosensing

Print ISBN: 978-3-319-75219-8

Electronic ISBN: 978-3-319-75220-4

Copyright Year: 2018

DOI
https://doi.org/10.1007/5346_2017_22

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