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Published in:
2014 | OriginalPaper | Chapter
Deterministic Modeling Spatio-Temporal Dynamics of Delay-Induced Circadian Oscillations in Neurospora crassa
Authors : Dmitry Bratsun, Andrey Zakharov
Published in: ISCS 2013: Interdisciplinary Symposium on Complex Systems
Publisher: Springer Berlin Heidelberg
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Abstract
We propose a spatially extended deterministic model with time delay for the circadian oscillations in the fungal species Neurospora crassa. The temporal behavior of the system is governed by a two variable model based on the nonlinear interplay between the FRQ and WCC proteins which are products of transcription of frequency and white collar genes. We show numerically that the model accounts for various features observed in experiments. Spatio-temporal protein patterns excited in Neurospora in complete darkness are studied for different initial conditions. It is shown that basal activation of transcription factors has a strong effect on pattern formation.