Skip to main content
Disciplines
Automotive Business IT + Informatics Construction + Real Estate Electrical Engineering + Electronics Energy + Sustainability Insurance + Risk Finance + Banking Management + Leadership Marketing + Sales Mechanical Engineering + Materials
Events
DE
EN
Books
Journals
Topic Page
Marketing
Start single access now
Access for companies
EXTENDED SEARCH
Log in
Top
Technical Physics
Published in: Technical Physics 10/2018

01-10-2018 | EXPERIMENTAL INSTRUMENTS AND TECHNIQUE

Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air

Authors: V. Kogan, A. S. Antonov, Yu. V. Chichagov, O. S. Victorova-Leclerc, I. V. Victorov, A. V. Kozlenok

Published in: Technical Physics | Issue 10/2018

Log in

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.
previous article A Hardware-Software Package for Analyzing the Gait of Patients with Normal Pressure Hydrocephalus

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

inform now
Literature
1.
W. Lindinger, A. Hansel, and A. Jordan, Int. J. Mass Spectrom. Ion Processes 173, 191 (1998).ADSCrossRef
2.
3.
4.
A. Amann and D. Smith, Volatile Biomarkers (Elsevier, 2013), Chaps. 3–4.
5.
A. W. Boots, J. J. B. N. Berkel, J. W. Dallinga, A. Smolinska, E. F. Wouters, and F. J. Schooten, J. Breath Res. 6, 027108 (2012).ADSCrossRef
6.
6th International Conference on Proton Transfer Reaction Mass Spectrometry and Its Applications, Ed. by A. Hanse and J. Dunkl (Innsbruck Univ. Press, Obergurgl, 2013).
7.
R. C. Johnson, R. G. Cooks, T. M. Allen, M. E. Cisper, and P. H. Hemberger, Mass Spectrom. Rev. 19, 1 (2000).ADSCrossRef
8.
9.
M. A. LaPack, J. C. Tou, V. L. McGuffin, and C. G. Enke, J. Membr. Sci. 86, 263 (1994).CrossRef
10.
R. A. Ketola, T. Kotiaho, M. E. Cisper, and T. M. Allen, J. Mass Spectrom. 37, 457 (2002).ADSCrossRef
11.
O. S. Viktorova, V. T. Kogan, S. A. Manninen, T. Kotiaho, R. A. Ketola, B. M. Dubenskii, S. P. Parinov, and O. V. Smirnov, J. Am. Soc. Mass Spectrom. 15, 823 (2004).CrossRef
12.
V. T. Kogan, O. S. Victorova, and I. V. Victorov, Instrum. Exp. Tech. 48, 85 (2005).CrossRef
13.
P. M. Llewellyn and D. P. Littlejohn, in Proc. Pittsburgh Conf. on Analytical Chemistry and Applied Spectroscopy, Pittsburgh, United States, 1966, p. 86.
14.
V. T. Kogan, A. V. Kozlenok, Yu. V. Chichagov, A.  S.  Antonov, D. S. Lebedev, A. A. Bogdanov, V.  S.  Moroshkin, A. V. Berezina, O. S. Viktorova-Leclerc, S. A. Vlasov, and Yu. V. Tubol’tsev, Tech. Phys. 60, 1549 (2015).CrossRef
15.
B. Buszewski, M. Kesy, T. Ligor, and A. Amann, Biomed. Chromatogr. 21, 553 (2007).CrossRef
16.
A. W. Boots, J. J. B. N. van Berkel, J. W. Dallinga, A. Smolinska, E. F. Wouters, and F. J. van Schooten, J. Breath Res. 6, 027108 (2012).ADSCrossRef
17.
W. Miekisch, J. K. Schubert, and G. F. Noeldge-Schomburg, Clin. Chim. Acta 347, 25 (2004).CrossRef
18.
19.
V. T. Kogan, A. S. Antonov, D. S. Lebedev, A. V. Kozlenok, S. A. Vlasov, Yu. V. Chichagov, and I. V. Victorov, Instrum. Exp. Tech. 56, 597 (2013).CrossRef
Metadata
Title
Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air
Authors
V. Kogan
A. S. Antonov
Yu. V. Chichagov
O. S. Victorova-Leclerc
I. V. Victorov
A. V. Kozlenok
Publication date
01-10-2018
Publisher
Pleiades Publishing
Published in
Technical Physics / Issue 10/2018
Print ISSN: 1063-7842
Electronic ISSN: 1090-6525
DOI
https://doi.org/10.1134/S1063784218100146

Other articles of this Issue 10/2018

Technical Physics 10/2018 Go to the issue

THEORETICAL AND MATHEMATICAL PHYSICS

Calculation of Self-Sputtering Yield under Ion Bombardment of Solids: Computer Simulation and Theory

BIOMEDICAL PHYSICS

A Hardware-Software Package for Analyzing the Gait of Patients with Normal Pressure Hydrocephalus

ELECTROPHYSICS, ELECTRON AND ION BEAMS, PHYSICS OF ACCELERATORS

Generation of High-Intensity Aluminum-Ion Beams at Low Energy

OPTICS

Lasing in 9.6-μm Quantum Cascade Lasers

PHYSICAL ELECTRONICS

Atomic Layer Deposition of Thin Films onto 3D Nanostructures: The Effect of Wall Tilt Angle and Aspect Ratio of Trenches

PHYSICAL SCIENCE OF MATERIALS

Nanopore Evolution Kinetics during Annealing of Submicrocrystalline Materials

Premium Partners

    Image Credits