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Published in:
1987 | OriginalPaper | Chapter
Effects of an Amino-Terminal Fragment of Substance P on Brain Dopamine and Serotonin Metabolism
Authors : M. E. Hall, P. DeArmey, J. M. Stewart
Published in: Substance P and Neurokinins
Publisher: Springer New York
Included in: Professional Book Archive
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Central or peripheral administration of substance P (SP) produces a number of effects on behavior. In mice, SP decreases isolation-induced aggressive [1] and nociceptive [2] behaviors. SP alters several measures of spontaneous motor behavior in rats and mice [3]. Intraventricular (ICIT) SP dramatically enhances groaning and scratching behavior in mice [4], but not rats [5], while locomotion, sniffing and hindlimb rearing behavior are enhanced in both species [6,7].