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Technical Physics
Published in: Technical Physics 9/2018

01-09-2018 | DEVELOPMENT OF PROCESS TECHNOLOGIES, DIAGNOSTIC METHODS, AND FUNCTIONAL MATERIALS AND STRUCTURES

Formation of Polyacrylamide and PEGDA Hydrogel Particles in a Microfluidic Flow Focusing Droplet Generator

Authors: D. V. Nozdriukhin, N. A. Filatov, A. A. Evstrapov, A. S. Bukatin

Published in: Technical Physics | Issue 9/2018

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Abstract

Monodisperse polymeric particles have great potential in biomedical and physical applications. Modern high-throughput droplet microfluidic technologies make it possible to produce monodisperse water-in-oil macroemulsions with desired properties. Polymerization in a macroemulsion transforms it to a suspension of microparticles. These particles may be viewed as containers for targeted delivery of drugs and also as bioink for 3D printing of tissues and organs. Conditions for formation of PEGDA and polyacrylamide particles using a microfluidic flow-focusing emulsion generator have been studied. Manufactured microparticles have been characterized by their geometrical sizes and mechanical properties. In addition, the diffusion escape of small molecules from microparticles has been studied using Rhodamine B fluorescent dye.
previous article The Mechanical Properties of Chitosan Fibers Obtained in Different Spinning Conditions by Coagulation Method
next article Self-Organization of a Bioactive Nanostructured Oxide Layer at the Surface of Sintered Titanium Sponge Powder Subjected to Electrochemical Anodization

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Metadata
Title
Formation of Polyacrylamide and PEGDA Hydrogel Particles in a Microfluidic Flow Focusing Droplet Generator
Authors
D. V. Nozdriukhin
N. A. Filatov
A. A. Evstrapov
A. S. Bukatin
Publication date
01-09-2018
Publisher
Pleiades Publishing
Published in
Technical Physics / Issue 9/2018
Print ISSN: 1063-7842
Electronic ISSN: 1090-6525
DOI
https://doi.org/10.1134/S1063784218090141

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