1995 | OriginalPaper | Chapter
Interference Effects in Multicomponent Chromatography
Author : Prof. Dr. Tingyue Gu
Published in: Mathematical Modeling and Scale-up of Liquid Chromatography
Publisher: Springer Berlin Heidelberg
Included in: Professional Book Archive
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Analytical chromatography usually involves small and dilute samples. Thus, interference effects among different sample components are often negligible. With the rapid growth of biotechnology, preparative- and large-scale chromatography become more and more important. High feed concentrations and large sample volumes are often used to increase productivity. In such cases, interference effects may no longer be ignored.