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Published in: Soft Computing 12/2010

01-10-2010 | Focus

Making decisions on brain tumor diagnosis by soft computing techniques

Authors: G. Farias, M. Santos, V. López

Published in: Soft Computing | Issue 12/2010

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Abstract

In this paper, a synergy of advanced signal processing and soft computing strategies is applied in order to identify different types of human brain tumors, as a help to confirm the histological diagnosis of experts and consequently to facilitate the decision about the correct treatment or the necessity of an operation. A computational tool has been developed that merges, on the one hand, wavelet transform to reduce the size of the biomedical spectra and to extract the main features, and on the other hand, Support Vector Machine and Neural Networks to classify them. The influence of some of the configuration parameters of each of those soft computing techniques on the clustering is analyzed. These two methods and another one based on medical knowledge are compared. The classification results obtained by these computational tools are promising specially taking into account that medical knowledge has not been considered and that the number of samples of each class is very low in some cases.

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Literature
go back to reference Daubechies I (1992) Ten lectures on wavelets: CBMS lectures series. SIAM, PhiladelphiaMATH Daubechies I (1992) Ten lectures on wavelets: CBMS lectures series. SIAM, PhiladelphiaMATH
go back to reference Demuth H, Beale M (1998) Neural network toolbox user’s guide. The MathWorks Inc, USA Demuth H, Beale M (1998) Neural network toolbox user’s guide. The MathWorks Inc, USA
go back to reference Duda RO, Hart PE, Stork D (2001) Pattern classification. Wiley, New York Duda RO, Hart PE, Stork D (2001) Pattern classification. Wiley, New York
go back to reference Farias G, Santos M (2005) Analysis of the wavelet transform parameters in images processing. LNCCS 2:51–54 Farias G, Santos M (2005) Analysis of the wavelet transform parameters in images processing. LNCCS 2:51–54
go back to reference Farias G, Santos M, López V (2008) Brain tumour diagnosis with wavelets and support vector machines. Proceedings of the 3rd IEEE international conference on intelligent systems and knowledge engineering, pp 1453–1459 Farias G, Santos M, López V (2008) Brain tumour diagnosis with wavelets and support vector machines. Proceedings of the 3rd IEEE international conference on intelligent systems and knowledge engineering, pp 1453–1459
go back to reference García-Martín ML, Hérigault G, Rémy CH, Farion R, Ballesteros P, Coles J, Cerdán S (2001) Mapping extracellular pH in rat brain gliomas “in vivo” by H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Res 61:6524–6531 García-Martín ML, Hérigault G, Rémy CH, Farion R, Ballesteros P, Coles J, Cerdán S (2001) Mapping extracellular pH in rat brain gliomas “in vivo” by H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Res 61:6524–6531
go back to reference Hagberg G (1998) From magnetic resonance spectroscopy to classification tumors: a review of pattern recognition methods. NMR Biomed 11:148–156CrossRef Hagberg G (1998) From magnetic resonance spectroscopy to classification tumors: a review of pattern recognition methods. NMR Biomed 11:148–156CrossRef
go back to reference Haykin S (1999) Neural networks: a comprehensive foundation, 2nd. edn. Prentice-Hall, Upper Saddle River, NJ Haykin S (1999) Neural networks: a comprehensive foundation, 2nd. edn. Prentice-Hall, Upper Saddle River, NJ
go back to reference Hore P (1983) Solvent suppression in Fourier Transform nuclear magn. reson. J Magn Reson 55:283–300 Hore P (1983) Solvent suppression in Fourier Transform nuclear magn. reson. J Magn Reson 55:283–300
go back to reference Howells SL, Maxwell R, Griffiths JR (1992) An investigation of tumor 1H NMR spectra by pattern recognition. NMR Biomed 5:59–64CrossRef Howells SL, Maxwell R, Griffiths JR (1992) An investigation of tumor 1H NMR spectra by pattern recognition. NMR Biomed 5:59–64CrossRef
go back to reference Kim I, Watada J, Shigaki I (2008) Complementary case-based reasoning and competitive fuzzy cognitive maps for advanced medical decision. Soft Comput 12:191–199 Kim I, Watada J, Shigaki I (2008) Complementary case-based reasoning and competitive fuzzy cognitive maps for advanced medical decision. Soft Comput 12:191–199
go back to reference Kinoshita Y, Yokota A (1997) Absolute concentrations of metabolites in human brain tumours using in vitro proton magn. reson. spectroscopy. NMR Biomed 10:2–12CrossRef Kinoshita Y, Yokota A (1997) Absolute concentrations of metabolites in human brain tumours using in vitro proton magn. reson. spectroscopy. NMR Biomed 10:2–12CrossRef
go back to reference Laguna P, Moody GB, García J, Goldberger AL, Mark RG (1999) Analysis of the ST-T complex using the KL transform: adaptative monitoring and alternant detection. Med Biol Eng Comput 37(2):175–189CrossRef Laguna P, Moody GB, García J, Goldberger AL, Mark RG (1999) Analysis of the ST-T complex using the KL transform: adaptative monitoring and alternant detection. Med Biol Eng Comput 37(2):175–189CrossRef
go back to reference Mallat SG (2001) A wavelet tour of signal processing, 2nd edn. Academic Press, San Diego Mallat SG (2001) A wavelet tour of signal processing, 2nd edn. Academic Press, San Diego
go back to reference Martínez-Pérez I, Maxwell RJ, Howells SL, van der Bogaart A, Mazucco R, Griffiths JR, Arús C (1995) Pattern recognition analysis of 1H NMR spectra from human brain tumours biopsies. Proceedings Soc magnetic resonance. 3rd annual meeting Abstract P1709 Martínez-Pérez I, Maxwell RJ, Howells SL, van der Bogaart A, Mazucco R, Griffiths JR, Arús C (1995) Pattern recognition analysis of 1H NMR spectra from human brain tumours biopsies. Proceedings Soc magnetic resonance. 3rd annual meeting Abstract P1709
go back to reference Maxwell RJ, Martínez-P. I, Cerdán S, Cabañas ME, Arús C, Moreno A, Capdevila A, Ferrer E, Bartomeus F, Aparicio A, Conesa G, Roda JM, Carceller F, Pascual JM, Howells SL, Mazzuco R, Griffiths J (1998) Pattern recognition analysis oh 1H NMR spectra from perchloric acid extracts of human brain tumor biopsies. Magn Reson Med 39:869–877 Maxwell RJ, Martínez-P. I, Cerdán S, Cabañas ME, Arús C, Moreno A, Capdevila A, Ferrer E, Bartomeus F, Aparicio A, Conesa G, Roda JM, Carceller F, Pascual JM, Howells SL, Mazzuco R, Griffiths J (1998) Pattern recognition analysis oh 1H NMR spectra from perchloric acid extracts of human brain tumor biopsies. Magn Reson Med 39:869–877
go back to reference Misiti M, Misiti Y, Oppenheim G, Poggi J-M (1997) Users Guide: Wavelet Toolbox for use with MATLAB. The MathWorks, Inc, Natick Misiti M, Misiti Y, Oppenheim G, Poggi J-M (1997) Users Guide: Wavelet Toolbox for use with MATLAB. The MathWorks, Inc, Natick
go back to reference Pascual J, Carceller F, Cerdán S, Roda JM (1998) Diagnóstico diferencial de tumores cerebrales “in vitro” por espectroscopia de resonancia magnética de protón. Método de los cocientes espectrales. Neurocirugía 9:4–10 Pascual J, Carceller F, Cerdán S, Roda JM (1998) Diagnóstico diferencial de tumores cerebrales “in vitro” por espectroscopia de resonancia magnética de protón. Método de los cocientes espectrales. Neurocirugía 9:4–10
go back to reference Peeling J, Sutherland G (1992) High-resolution 1H NMR spectroscopy studies of extracts of human cerebral neoplasm. Magn Reson Med 24:123–136CrossRef Peeling J, Sutherland G (1992) High-resolution 1H NMR spectroscopy studies of extracts of human cerebral neoplasm. Magn Reson Med 24:123–136CrossRef
go back to reference Rafiei D, Mendelzon A (1998) Efficient retrieval of similar time sequences using DFT. Proceedings of the 5th international conference on foundations of data organization, pp 249–257 Rafiei D, Mendelzon A (1998) Efficient retrieval of similar time sequences using DFT. Proceedings of the 5th international conference on foundations of data organization, pp 249–257
go back to reference Roda JM, Pascual JM, Carceller F, Gonzalez-Llanos F (2000) Nonhistological diagnosis of human cerebral tumors by 1H magnetic resonance spectroscopy and amino acid analysis. Clin Cancer Res 6:3983–3993 Roda JM, Pascual JM, Carceller F, Gonzalez-Llanos F (2000) Nonhistological diagnosis of human cerebral tumors by 1H magnetic resonance spectroscopy and amino acid analysis. Clin Cancer Res 6:3983–3993
go back to reference Rojas R (1995) Neural networks: a systematic introduction. Springer, New York Rojas R (1995) Neural networks: a systematic introduction. Springer, New York
go back to reference Ruiz-Molina JC, Navarro-Moreno J, Oya A (2001) Signal detection using approximate Karhunen-Loève expansions. IEEE Trans Inf Theory 47(4):1672–1680MATHCrossRefMathSciNet Ruiz-Molina JC, Navarro-Moreno J, Oya A (2001) Signal detection using approximate Karhunen-Loève expansions. IEEE Trans Inf Theory 47(4):1672–1680MATHCrossRefMathSciNet
go back to reference Somorjai RL, Dolenko B, Nikulin AK, Pizzi N, Scarth G, Zhilkin P, Halliday W, Fewer D, Hill N, Ross I, West M, Smith ICP, Donnelly SM, Kuesel AC, Bière KM (1996) Classification of 1H MR spectra of human brain neoplasms: the influence of preprocessing and computerized consensus diagnosis on classification accuracy. J Magn Reson Imaging 6:437–444CrossRef Somorjai RL, Dolenko B, Nikulin AK, Pizzi N, Scarth G, Zhilkin P, Halliday W, Fewer D, Hill N, Ross I, West M, Smith ICP, Donnelly SM, Kuesel AC, Bière KM (1996) Classification of 1H MR spectra of human brain neoplasms: the influence of preprocessing and computerized consensus diagnosis on classification accuracy. J Magn Reson Imaging 6:437–444CrossRef
go back to reference Tate AR (1997) Statistical pattern recognition for the analysis of biomedical magnetic resonance spectra. J Magn Reson Anal 3:63–78 Tate AR (1997) Statistical pattern recognition for the analysis of biomedical magnetic resonance spectra. J Magn Reson Anal 3:63–78
go back to reference Tate AR, Griffiths JR, Martínez PI, Moreno A, Barba I, Cabañas M, Watson D, Alonso J, Bartumeus F, Isamat F, Ferrer I, Vila F, Ferrer E, Capdevilla A, Arús C (1998) Towards a method for automated classification of 1H MRS spectra from brain tumours. NMR Biomed 11:177–191CrossRef Tate AR, Griffiths JR, Martínez PI, Moreno A, Barba I, Cabañas M, Watson D, Alonso J, Bartumeus F, Isamat F, Ferrer I, Vila F, Ferrer E, Capdevilla A, Arús C (1998) Towards a method for automated classification of 1H MRS spectra from brain tumours. NMR Biomed 11:177–191CrossRef
go back to reference Therrien CW (1992) Discrete random signals and statistical signal processing. Prentice-Hall, Upper Saddle River, NJ Therrien CW (1992) Discrete random signals and statistical signal processing. Prentice-Hall, Upper Saddle River, NJ
go back to reference Unser M, Aldroubi A (1995) A review of wavelets in biomedical applications. Proc IEEE 48:626–638 Unser M, Aldroubi A (1995) A review of wavelets in biomedical applications. Proc IEEE 48:626–638
go back to reference Vapnik VN (2000) The nature of statistical learning theory, 2nd edn. Springer, New York Vapnik VN (2000) The nature of statistical learning theory, 2nd edn. Springer, New York
go back to reference Wen X, Zhang H, Xu X, Quan J (2009) A new watermarking approach based on probabilistic neural network in wavelet domain. Soft Comput 13:355–360CrossRef Wen X, Zhang H, Xu X, Quan J (2009) A new watermarking approach based on probabilistic neural network in wavelet domain. Soft Comput 13:355–360CrossRef
go back to reference Yin P, Sun F, Wang C, Liu H (2008) An adaptive feature fusion framework for multi-class classification based on SVM. Soft Comput 12:685–691CrossRef Yin P, Sun F, Wang C, Liu H (2008) An adaptive feature fusion framework for multi-class classification based on SVM. Soft Comput 12:685–691CrossRef
Metadata
Title
Making decisions on brain tumor diagnosis by soft computing techniques
Authors
G. Farias
M. Santos
V. López
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
Soft Computing / Issue 12/2010
Print ISSN: 1432-7643
Electronic ISSN: 1433-7479
DOI
https://doi.org/10.1007/s00500-009-0495-0

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