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Microsystem Technologies

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16-07-2016 | Review Paper

Microfluidic-based biosensor: signal enhancement by gold nanoparticle

Authors: Thangavel Lakshmipriya, Uda Hashim, Subash C. B. Gopinath, N. Azizah

Published in: Microsystem Technologies | Issue 10/2016

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Abstract

Biosensor is an analytical device to detect the biomolecules assisted by the transducer and physicochemical detector. A good biosensor is expecting to be with low cost, easy to perform and identify the results without prior experience. In addition, a good biosensor has two main key characteristics such as sensitivity and specificity; these are mainly determined by the affinity of biomolecules with the assistance of sensing system. Microfluidic-based lab-on-chip is one of the fast growing technologies in the field of biosensor bring the positive characteristics with a fast delivery set-up. On the other hand, gold nanoparticle (GNP) is the powerful tool to enhance the biomolecular detection with higher sensitivity and it has been proved for the effective applications with different sensors. In this review, we discussed the applications of microfluidic-based delivery and GNP for biosensing with the new level of developments, which elevate a step ahead.

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Title: Microfluidic-based biosensor: signal enhancement by gold nanoparticle
Authors: Thangavel Lakshmipriya
Uda Hashim
Subash C. B. Gopinath
N. Azizah
Publication date: 16-07-2016
Publisher: Springer Berlin Heidelberg
Published in: Microsystem Technologies / Issue 10/2016
Print ISSN: 0946-7076
Electronic ISSN: 1432-1858
DOI: https://doi.org/10.1007/s00542-016-3074-1

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