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Journal of Nanoparticle Research

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01-02-2017 | Research Paper

Modeling drug release from functionalized magnetic nanoparticles actuated by non-heating low frequency magnetic field

Authors: Y. Golovin, D. Golovin, N. Klyachko, A. Majouga, A. Kabanov

Published in: Journal of Nanoparticle Research | Issue 2/2017

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Abstract

Various plausible acceleration mechanisms of drug release from nanocarriers composed of a single-domain magnetic nanoparticle core with attached long macromolecule chains activated by low frequency non-heating alternating magnetic field (AMF) are discussed. The most important system characteristics affecting the AMF exposure impact are determined. Impact of several reasonable mechanisms is estimated analytically or obtained using numerical modeling. Some conditions providing manifold release acceleration as a result from exposure in AMF are found.

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Title: Modeling drug release from functionalized magnetic nanoparticles actuated by non-heating low frequency magnetic field
Authors: Y. Golovin
D. Golovin
N. Klyachko
A. Majouga
A. Kabanov
Publication date: 01-02-2017
Publisher: Springer Netherlands
Published in: Journal of Nanoparticle Research / Issue 2/2017
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-017-3754-5

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