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2016 | OriginalPaper | Chapter

6. Modern Polysaccharides and Its Current Advancements

Author : Saurabh Bhatia

Published in: Systems for Drug Delivery

Publisher: Springer International Publishing

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Abstract

Polysaccharides based nanomaterials have diverse applications in biomedical research. This chapter covers one of the major achievements in modification of polysaccharides using microwave irradiation and cationization methods. Additionally chapter focused on mucoadhesive polysaccharides and its recent advancement in nano drug delivery system. Applications such as gene transfection, bone regeneration and vaccine delivery are also separately discussed.

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Literature
1.
go back to reference Janes KA, Calvo P, Alonso MJ. Polysaccharide colloidal particles as delivery systems for macromolecules. Adv Drug Deliv Rev. 2001;47:83–97.CrossRef Janes KA, Calvo P, Alonso MJ. Polysaccharide colloidal particles as delivery systems for macromolecules. Adv Drug Deliv Rev. 2001;47:83–97.CrossRef
2.
go back to reference Shogren RL, Bagley EB. Natural polymers as advanced materials: some research needs and directions. In: Iman SH, Greene RV, Zaidi BR, editors. Biopolymers. Utilizing nature’s advanced materials, ACS symposium series 723. Cary, USA: Oxford University Press; 1999. p. 2–11. Shogren RL, Bagley EB. Natural polymers as advanced materials: some research needs and directions. In: Iman SH, Greene RV, Zaidi BR, editors. Biopolymers. Utilizing nature’s advanced materials, ACS symposium series 723. Cary, USA: Oxford University Press; 1999. p. 2–11.
3.
go back to reference Kaplan DL. Introduction to polymers from renewable resources. In: Kaplan DL, editor. Biopolymers from renewable resources. Berlin, Germany: Springer Verlag; 1998. p. 1–29.CrossRef Kaplan DL. Introduction to polymers from renewable resources. In: Kaplan DL, editor. Biopolymers from renewable resources. Berlin, Germany: Springer Verlag; 1998. p. 1–29.CrossRef
4.
go back to reference Yannas IV. Natural materials. In: Hoffman AS, Schoen FJ, Lemons JE, Ratner BD, editors. Biomaterials science. An introduction to materials in medicine. San Diego: Academic; 1996. p. 84–94. Yannas IV. Natural materials. In: Hoffman AS, Schoen FJ, Lemons JE, Ratner BD, editors. Biomaterials science. An introduction to materials in medicine. San Diego: Academic; 1996. p. 84–94.
5.
go back to reference Hon DS. Cellulose and its derivatives: structures, reactions, and medical uses. In: Dumitriu S, editor. Polysaccharides in medicinal applications. New York, USA: Marcel Dekker; 1996. p. 87–105. Hon DS. Cellulose and its derivatives: structures, reactions, and medical uses. In: Dumitriu S, editor. Polysaccharides in medicinal applications. New York, USA: Marcel Dekker; 1996. p. 87–105.
6.
go back to reference Okajima K. Role of molecular characteristics on some physiological properties of cellulose derivatives. In: Kennedy JF, Phillips GO, Williams PA, editors. Cellulose: structural and functional aspects. Chichester, UK: Ellis Horwood; 1989. p. 439–46. Okajima K. Role of molecular characteristics on some physiological properties of cellulose derivatives. In: Kennedy JF, Phillips GO, Williams PA, editors. Cellulose: structural and functional aspects. Chichester, UK: Ellis Horwood; 1989. p. 439–46.
7.
go back to reference Ikada Y. Biomedical applications of cellulose membranes. Idem. p. 447–455. Ikada Y. Biomedical applications of cellulose membranes. Idem. p. 447–455.
8.
go back to reference Miyamoto T, Takahashi S, Ito H, Inagaki H, Noishiki Y. Tissue biocompatibility of cellulose and its derivatives. J Biomed Mater Res. 1989;23:125–33.CrossRef Miyamoto T, Takahashi S, Ito H, Inagaki H, Noishiki Y. Tissue biocompatibility of cellulose and its derivatives. J Biomed Mater Res. 1989;23:125–33.CrossRef
9.
go back to reference Ouchi T, Nishizawa H, Ohya Y. Aggregation phenomenon of PEG-grafted chitosan in aqueous solution. Polymer. 1998;39:5171–5.CrossRef Ouchi T, Nishizawa H, Ohya Y. Aggregation phenomenon of PEG-grafted chitosan in aqueous solution. Polymer. 1998;39:5171–5.CrossRef
10.
go back to reference Yoksan R, Matsusaki M, Akashi M, Chirachanchai S. Controlled hydrophobic/ hydrophilic chitosan: colloidal phenomena and nanosphere formation. Colloid Polym Sci. 2004;282:337–42.CrossRef Yoksan R, Matsusaki M, Akashi M, Chirachanchai S. Controlled hydrophobic/ hydrophilic chitosan: colloidal phenomena and nanosphere formation. Colloid Polym Sci. 2004;282:337–42.CrossRef
11.
go back to reference Jeong YI, et al. Polyion complex micelles composed of all-trans retinoic acid and poly (ethylene glycol)-grafted-citosan. J Pharm Sci. 2006;95:2348–60.CrossRef Jeong YI, et al. Polyion complex micelles composed of all-trans retinoic acid and poly (ethylene glycol)-grafted-citosan. J Pharm Sci. 2006;95:2348–60.CrossRef
12.
go back to reference Choisnard L, Geze A, Putaux JL, Wong YS, Wouessidjewe D. Nanoparticles of beta-cyclodextrin esters obtained by self-assembling of biotransesterified betacyclodextrins. Biomacromolecules. 2006;7:515–20.CrossRef Choisnard L, Geze A, Putaux JL, Wong YS, Wouessidjewe D. Nanoparticles of beta-cyclodextrin esters obtained by self-assembling of biotransesterified betacyclodextrins. Biomacromolecules. 2006;7:515–20.CrossRef
13.
go back to reference Chen XG, Lee CM, Park HJ. OM emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system. J Agric Food Chem. 2003;51:3135–9.CrossRef Chen XG, Lee CM, Park HJ. OM emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system. J Agric Food Chem. 2003;51:3135–9.CrossRef
14.
go back to reference Jiang GB, Quan D, Liao K, Wang H. Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery. Mol Pharmacol. 2006;3:152–60.CrossRef Jiang GB, Quan D, Liao K, Wang H. Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery. Mol Pharmacol. 2006;3:152–60.CrossRef
15.
go back to reference Zhang J, Chen XG, Li YY, Liu CS. Self-assembled nanoparticles based on hydrophobically modified chitosan as carriers for doxorubicin. Nanomed Nanotechnol. 2007;3:258–65.CrossRef Zhang J, Chen XG, Li YY, Liu CS. Self-assembled nanoparticles based on hydrophobically modified chitosan as carriers for doxorubicin. Nanomed Nanotechnol. 2007;3:258–65.CrossRef
16.
go back to reference Lemarchand C, Couvreur P, Besnard M, Costantini D, Gref R. Novel polyesterpolysaccharide nanoparticles. Pharm Res. 2003;20:1284–92.CrossRef Lemarchand C, Couvreur P, Besnard M, Costantini D, Gref R. Novel polyesterpolysaccharide nanoparticles. Pharm Res. 2003;20:1284–92.CrossRef
17.
go back to reference Choi SH, Lee JH, Choi SM, Park TG. Thermally reversible pluronic/heparin nanocapsules exhibiting 1000-fold volume transition. Langmuir. 2006;22:1758–62.CrossRef Choi SH, Lee JH, Choi SM, Park TG. Thermally reversible pluronic/heparin nanocapsules exhibiting 1000-fold volume transition. Langmuir. 2006;22:1758–62.CrossRef
18.
go back to reference Han SK, Lee JH, Kim D, Cho SH, Yuk SH. Hydrophilized poly(lactide-coglycolide) nanoparticles with core/shell structure for protein delivery. Sci Technol Adv Mater. 2005;6:468–74.CrossRef Han SK, Lee JH, Kim D, Cho SH, Yuk SH. Hydrophilized poly(lactide-coglycolide) nanoparticles with core/shell structure for protein delivery. Sci Technol Adv Mater. 2005;6:468–74.CrossRef
19.
go back to reference Kuroda K, Fujimoto K, Sunamoto J, Akiyoshi K. Hierarchical self-assembly of hydrophobically modified pullulan in water: gelation by networks of nanoparticles. Langmuir. 2002;18:3780–6.CrossRef Kuroda K, Fujimoto K, Sunamoto J, Akiyoshi K. Hierarchical self-assembly of hydrophobically modified pullulan in water: gelation by networks of nanoparticles. Langmuir. 2002;18:3780–6.CrossRef
20.
go back to reference Wang YS, Liu LR, Jiang Q, Zhang QQ. Self-aggregated nanoparticles of cholesterol-modified chitosan conjugate as a novel carrier of epirubicin. Eur Polym J. 2007;43:43–51.CrossRef Wang YS, Liu LR, Jiang Q, Zhang QQ. Self-aggregated nanoparticles of cholesterol-modified chitosan conjugate as a novel carrier of epirubicin. Eur Polym J. 2007;43:43–51.CrossRef
21.
go back to reference Akiyoshi K, Deguchi S, Tajima H, Nishikawa T, Sunamoto J. Microscopic structure and thermo responsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide. Macromolecules. 1997;30:857–61.CrossRef Akiyoshi K, Deguchi S, Tajima H, Nishikawa T, Sunamoto J. Microscopic structure and thermo responsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide. Macromolecules. 1997;30:857–61.CrossRef
22.
go back to reference Lee KY, Jo WH, Kwon IC, Kim YH, Jeong SY. Structural determination and interior polarity of self-aggregates prepared from deoxycholic acid-modified chitosan in water. Macromolecules. 1998;31:378–83.CrossRef Lee KY, Jo WH, Kwon IC, Kim YH, Jeong SY. Structural determination and interior polarity of self-aggregates prepared from deoxycholic acid-modified chitosan in water. Macromolecules. 1998;31:378–83.CrossRef
23.
go back to reference Kim K, Kwon S, Park JH, Chung H, Jeong SY, Kwon IC. Physicochemical characterizations of self-assembled nanoparticles of glycol chitosan-deoxycholic acid conjugates. Biomacromolecules. 2005;6:1154–8.CrossRef Kim K, Kwon S, Park JH, Chung H, Jeong SY, Kwon IC. Physicochemical characterizations of self-assembled nanoparticles of glycol chitosan-deoxycholic acid conjugates. Biomacromolecules. 2005;6:1154–8.CrossRef
24.
go back to reference Park K, Kim JH, Nam YS, Lee S, Nam HY, Kim K, Park JH, Kim IS, Choi K, Kim SY, Kwon IC. Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles. J Control Release. 2007;122:305–14.CrossRef Park K, Kim JH, Nam YS, Lee S, Nam HY, Kim K, Park JH, Kim IS, Choi K, Kim SY, Kwon IC. Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles. J Control Release. 2007;122:305–14.CrossRef
25.
go back to reference Lee M, et al. Size control of self-assembled nanoparticles by an emulsion/ solvent evaporation method. Colloid Polym Sci. 2006;284:506–12.CrossRef Lee M, et al. Size control of self-assembled nanoparticles by an emulsion/ solvent evaporation method. Colloid Polym Sci. 2006;284:506–12.CrossRef
26.
go back to reference Park JH, et al. Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activity. Biomaterials. 2006;27:119–26.CrossRef Park JH, et al. Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activity. Biomaterials. 2006;27:119–26.CrossRef
27.
go back to reference Na K, Lee TB, Park KH, Shin EK, Lee YB, Cho HK. Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anticancer drug delivery system. Eur J Pharm Sci. 2003;18:165–73.CrossRef Na K, Lee TB, Park KH, Shin EK, Lee YB, Cho HK. Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anticancer drug delivery system. Eur J Pharm Sci. 2003;18:165–73.CrossRef
28.
go back to reference Park JS, et al. Nacetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release. J Control Release. 2006;115:37–45.CrossRef Park JS, et al. Nacetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release. J Control Release. 2006;115:37–45.CrossRef
29.
go back to reference Passirani C, Barratt G, Devissaguet JP, Labarre D. Long-circulating nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate). Pharm Res. 1998;15:1046–50.CrossRef Passirani C, Barratt G, Devissaguet JP, Labarre D. Long-circulating nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate). Pharm Res. 1998;15:1046–50.CrossRef
30.
go back to reference Yang SC, Ge HX, Hu Y, Jiang XQ, Yang CZ. Formation of positively charged poly (butyl cyanoacrylate) nanoparticles stabilized with chitosan. Colloid Polym Sci. 2000;278:285–92.CrossRef Yang SC, Ge HX, Hu Y, Jiang XQ, Yang CZ. Formation of positively charged poly (butyl cyanoacrylate) nanoparticles stabilized with chitosan. Colloid Polym Sci. 2000;278:285–92.CrossRef
31.
go back to reference Bertholon I, Vauthier C, Labarre D. Complement activation by core-shell poly (isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide. Pharm Res. 2006;23:1313–23.CrossRef Bertholon I, Vauthier C, Labarre D. Complement activation by core-shell poly (isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide. Pharm Res. 2006;23:1313–23.CrossRef
32.
go back to reference Bravo-Osuna I, Schmitz T, Bernkop-Schnurch A, Vauthier C, Ponchel G. Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles. Int J Pharm. 2006;316:170–5.CrossRef Bravo-Osuna I, Schmitz T, Bernkop-Schnurch A, Vauthier C, Ponchel G. Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles. Int J Pharm. 2006;316:170–5.CrossRef
33.
go back to reference Chauvierre C, Labarre D, Couvreur P, Vauthier C. Novel polysaccharide-decorated poly(isobutyl cyanoacrylate) nanoparticles. Pharm Res. 2003;20:1786–93.CrossRef Chauvierre C, Labarre D, Couvreur P, Vauthier C. Novel polysaccharide-decorated poly(isobutyl cyanoacrylate) nanoparticles. Pharm Res. 2003;20:1786–93.CrossRef
34.
go back to reference Shukla RK, Tiwari A. Carbohydrate polymers: applications and recent advances in delivering drugs to the colon. Carbohydr Polym. 2012;88:399–416.CrossRef Shukla RK, Tiwari A. Carbohydrate polymers: applications and recent advances in delivering drugs to the colon. Carbohydr Polym. 2012;88:399–416.CrossRef
35.
go back to reference Widner B, Behr R, Von SD, Tang M, Heu T, Sloma A, et al. Hyaluronic acid production in Bacillus subtilis. Appl Environ Microbiol. 2005;71:3747–52.CrossRef Widner B, Behr R, Von SD, Tang M, Heu T, Sloma A, et al. Hyaluronic acid production in Bacillus subtilis. Appl Environ Microbiol. 2005;71:3747–52.CrossRef
36.
go back to reference Naessens M, Cerdobbel A, Soetaert W, Vandamme EJ. Leuconostoc dextransucrase and dextran: production, properties and applications. J Chem Technol Biotechnol. 2005;80:845–60.CrossRef Naessens M, Cerdobbel A, Soetaert W, Vandamme EJ. Leuconostoc dextransucrase and dextran: production, properties and applications. J Chem Technol Biotechnol. 2005;80:845–60.CrossRef
37.
go back to reference Coutinho DF, Sant SV, Shin H, Oliveira JT, Gomes ME, Neves NM, et al. Modified Gellan Gum hydrogels with tunable physical and mechanical properties. Biomaterials. 2010;31:7494–502.CrossRef Coutinho DF, Sant SV, Shin H, Oliveira JT, Gomes ME, Neves NM, et al. Modified Gellan Gum hydrogels with tunable physical and mechanical properties. Biomaterials. 2010;31:7494–502.CrossRef
38.
go back to reference Wang Q, Jonathan S, Robert D, Linhardt J. Synthesis and application of carbohydrate-containing polymers. Chem Mater. 2002;14:3232–44.CrossRef Wang Q, Jonathan S, Robert D, Linhardt J. Synthesis and application of carbohydrate-containing polymers. Chem Mater. 2002;14:3232–44.CrossRef
39.
go back to reference Mano JF, Silva GA, Azevedo HS, Malafaya PB, Sousa RA, Silva SS, et al. Natural origin biodegradable systems in tissue engineering and regenerative medicine: Present status and some moving trends. J R Soc Interface. 2007;4:999–1030.CrossRef Mano JF, Silva GA, Azevedo HS, Malafaya PB, Sousa RA, Silva SS, et al. Natural origin biodegradable systems in tissue engineering and regenerative medicine: Present status and some moving trends. J R Soc Interface. 2007;4:999–1030.CrossRef
40.
go back to reference Ramaprasad AT, Rao V, Sanjeev G, Ramanani SP, Sabharwal S. Grafting of polyaniline onto the radiation crosslinked chitosan. Synth Met. 2009;159:1983–90.CrossRef Ramaprasad AT, Rao V, Sanjeev G, Ramanani SP, Sabharwal S. Grafting of polyaniline onto the radiation crosslinked chitosan. Synth Met. 2009;159:1983–90.CrossRef
41.
go back to reference Crescenzi V, Dentini M, Risica D, Spadoni S, Skjåk-Bræk G, Capitani D, Mannina L, Viel S. C(6)-oxidationfollowedbyC(5)-epimerization of guar gum studied by high field NMR. Biomacromolecules. 2004;5:537–46.CrossRef Crescenzi V, Dentini M, Risica D, Spadoni S, Skjåk-Bræk G, Capitani D, Mannina L, Viel S. C(6)-oxidationfollowedbyC(5)-epimerization of guar gum studied by high field NMR. Biomacromolecules. 2004;5:537–46.CrossRef
42.
go back to reference Galanos C, Luderitz O, Himmelspach K. The partial acid hydrolysis of polysaccharides: a new method for obtaining oligosaccharides in high yield. Eur J Biochem. 2004;8:332–6.CrossRef Galanos C, Luderitz O, Himmelspach K. The partial acid hydrolysis of polysaccharides: a new method for obtaining oligosaccharides in high yield. Eur J Biochem. 2004;8:332–6.CrossRef
43.
go back to reference Prado HJ, Matulewicz MC. Cationization of polysaccharides: A path to greener derivatives with many industrial applications. Eur Polym J. 2014;52:53–75.CrossRef Prado HJ, Matulewicz MC. Cationization of polysaccharides: A path to greener derivatives with many industrial applications. Eur Polym J. 2014;52:53–75.CrossRef
44.
go back to reference Šimkovic I. What could be greener than composites made from polysaccharides? Carbohydr Polym. 2008;74:759–62.CrossRef Šimkovic I. What could be greener than composites made from polysaccharides? Carbohydr Polym. 2008;74:759–62.CrossRef
45.
go back to reference Lee JW, Park JH, Robinson JR. Bioadhesive-based dosage forms: the next generation. J Pharm Sci. 2000;89:850–66.CrossRef Lee JW, Park JH, Robinson JR. Bioadhesive-based dosage forms: the next generation. J Pharm Sci. 2000;89:850–66.CrossRef
46.
go back to reference Langoth N, Kalbe J, Bernkop-Schnurch A. Development of buccal drug delivery systems based on a thiolated polymer. Int J Pharm. 2003;252:141–8.CrossRef Langoth N, Kalbe J, Bernkop-Schnurch A. Development of buccal drug delivery systems based on a thiolated polymer. Int J Pharm. 2003;252:141–8.CrossRef
47.
go back to reference Marschutz MK, Bernkop-Schnurch A. Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) and their influence on mucoadhesion. Eur J Pharm Sci. 2002;15:387–94.CrossRef Marschutz MK, Bernkop-Schnurch A. Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) and their influence on mucoadhesion. Eur J Pharm Sci. 2002;15:387–94.CrossRef
48.
go back to reference Kast CE, Bernkop-Schnurch A. Thiolated polymers– thiomers: development and in vitro evaluation of chitosan– thioglycolic acid conjugates. Biomaterials. 2001;22:2345–52.CrossRef Kast CE, Bernkop-Schnurch A. Thiolated polymers– thiomers: development and in vitro evaluation of chitosan– thioglycolic acid conjugates. Biomaterials. 2001;22:2345–52.CrossRef
49.
go back to reference Lehr CM. Lectin-mediated drug delivery: the second generation of bioadhesives. J Control Release. 2000;65:19–29.CrossRef Lehr CM. Lectin-mediated drug delivery: the second generation of bioadhesives. J Control Release. 2000;65:19–29.CrossRef
50.
go back to reference Rossi S, Sandri G, Ferrari F, Bonferoni MC, Caramella C. Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid. Pharm Dev Technol. 2003;8:199–208.CrossRef Rossi S, Sandri G, Ferrari F, Bonferoni MC, Caramella C. Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid. Pharm Dev Technol. 2003;8:199–208.CrossRef
51.
go back to reference Ikinci G, Senel S, AkVncVbay H, Kas S, Ercis S, Wilson CG, HVncal AA. Effect of chitosan on a periodontal pathogen Porphyromonas gingivalis. Int J Pharm. 2002;235:121–7.CrossRef Ikinci G, Senel S, AkVncVbay H, Kas S, Ercis S, Wilson CG, HVncal AA. Effect of chitosan on a periodontal pathogen Porphyromonas gingivalis. Int J Pharm. 2002;235:121–7.CrossRef
52.
go back to reference Senel S, Ikinci G, Kas S, V-Rad AY, Sargon MF, HVncal AA. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery. Int J Pharm. 2000;193:197–203.CrossRef Senel S, Ikinci G, Kas S, V-Rad AY, Sargon MF, HVncal AA. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery. Int J Pharm. 2000;193:197–203.CrossRef
53.
go back to reference Artusi M, Santi P, Colombo P, Junginger HE. Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. Int J Pharm. 2003;250:203–13.CrossRef Artusi M, Santi P, Colombo P, Junginger HE. Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. Int J Pharm. 2003;250:203–13.CrossRef
54.
go back to reference Minabe M, Takeuchi K, Tamura T, Hori T, Umemoto T. Subgingival administration of tetracycline on a collagen film. J Periodontol. 1989;60:552–6.CrossRef Minabe M, Takeuchi K, Tamura T, Hori T, Umemoto T. Subgingival administration of tetracycline on a collagen film. J Periodontol. 1989;60:552–6.CrossRef
55.
go back to reference Lopez CR, Portero A, Vila-Jato JL, Alonso MJ. Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery. J Control Release. 1998;55:143–52.CrossRef Lopez CR, Portero A, Vila-Jato JL, Alonso MJ. Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery. J Control Release. 1998;55:143–52.CrossRef
56.
go back to reference Ritschel WA, Ritschel GB, Forusz H, Kraeling M. Buccal absorption of insulin in the dog. Res Commun Chem Pathol Pharmacol. 1989;63:53–67. Ritschel WA, Ritschel GB, Forusz H, Kraeling M. Buccal absorption of insulin in the dog. Res Commun Chem Pathol Pharmacol. 1989;63:53–67.
57.
go back to reference Ilango R, Kavimani S, Mullaicharam AR, Jayakar B. In vitro studies on buccal strips of glibenclamide using chitosan. Indian J Pharm Sci. 1997;59:232–5. Ilango R, Kavimani S, Mullaicharam AR, Jayakar B. In vitro studies on buccal strips of glibenclamide using chitosan. Indian J Pharm Sci. 1997;59:232–5.
58.
go back to reference Khan W, Hosseinkhani H, Ickowicz D, Hong PD, Yu DS, Dom AJ. Polysaccharide gene transfection agents. Acta Biomater. 2012;8:4224–32.CrossRef Khan W, Hosseinkhani H, Ickowicz D, Hong PD, Yu DS, Dom AJ. Polysaccharide gene transfection agents. Acta Biomater. 2012;8:4224–32.CrossRef
59.
go back to reference Sosnik A, Neves J, Sarmento B. Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review. Prog Polym Sci. 2014;2030–2075:39. Sosnik A, Neves J, Sarmento B. Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review. Prog Polym Sci. 2014;2030–2075:39.
60.
go back to reference Yue H, Ma G. Polymeric micro/nanoparticles: particle design and potential vaccine delivery applications. Vaccine. 2015;33:5927–36.CrossRef Yue H, Ma G. Polymeric micro/nanoparticles: particle design and potential vaccine delivery applications. Vaccine. 2015;33:5927–36.CrossRef
61.
go back to reference Simkovic I. Unexplored possibilities of all-polysaccharide composites. Carbohydr Polym. 2013;95:697–715.CrossRef Simkovic I. Unexplored possibilities of all-polysaccharide composites. Carbohydr Polym. 2013;95:697–715.CrossRef
62.
go back to reference Gupta S, Sharma P, Soni PL. Carboxymethylation of Cassia occidentalis seed gum. J Appl Polym Sci. 2004;94:1606–11.CrossRef Gupta S, Sharma P, Soni PL. Carboxymethylation of Cassia occidentalis seed gum. J Appl Polym Sci. 2004;94:1606–11.CrossRef
63.
go back to reference Edgar KJ, Buchanan CM, Debenham JS, Rundquist PA, Seiler BD, Shelton MC, Tindall D. Advances in cellulose ester performance and application. Prog Polym Sci. 2001;26:1605–88.CrossRef Edgar KJ, Buchanan CM, Debenham JS, Rundquist PA, Seiler BD, Shelton MC, Tindall D. Advances in cellulose ester performance and application. Prog Polym Sci. 2001;26:1605–88.CrossRef
64.
go back to reference Sand A, Yadav M, Mishra DK, Behari K. Modification of alginate by grafting of N-vinyl-2-pyrrolidone and studies of physicochemical properties in terms of swelling capacity, metal-ion uptake and flocculation. Carbohydr Polym. 2010;80:1147–54.CrossRef Sand A, Yadav M, Mishra DK, Behari K. Modification of alginate by grafting of N-vinyl-2-pyrrolidone and studies of physicochemical properties in terms of swelling capacity, metal-ion uptake and flocculation. Carbohydr Polym. 2010;80:1147–54.CrossRef
Metadata
Title
Modern Polysaccharides and Its Current Advancements
Author
Saurabh Bhatia
Copyright Year
2016
DOI
https://doi.org/10.1007/978-3-319-41926-8_6

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