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Polymer Science, Series A

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01-05-2019 | MEDICAL POLYMERS

Mucoadhesive Polymer Carriers of Intranasal Medicines

Authors: I. L. Valuev, M. Yu. Gorshkova, L. V. Vanchugova, L. I. Valuev

Published in: Polymer Science, Series A | Issue 3/2019

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Abstract

The kinetics of tyrosine and phenylalanine release from mucoadhesive solutions of polyacrylamide and acrylamide–acrylic acid copolymer adhered to the surface of a polymer hydrogel has been studied. It has been shown that the time of solution retention on the surface exceeds the time of the complete release of amino acids by several times. These results demonstrate the fundamental possibility of creation of intranasal preparations providing the delivery to the brain at rapid release of the drug from a polymer composition adhered to the mucosa of the nose.

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A. C. Leary, M. Dowling, K. Cussen, J. O’Brien, and R. M. Stote, J. Diabetes Sci. Technol. 2, 1054 (2008).CrossRefPubMedPubMedCentral

A. M. Privalova, N. V. Gulyaeva, and T. V. Bukreeva, Neurochem. J. 6, 77 (2012).CrossRef

L. S. Kokov, V. N. Tsygankov, K. V. Petrushin, and V. M. Luchkin, in Proceedings of 2nd International Conference “Modern Technologies adn Possibilities of Reconstructive and Aesthetic Surgery”, Moscow, Russia, 2010 (Moscow, 2010), p. 84.

M. A. Odeniyi, N. H. Khan, and K. K. Peh, Acta Polym. Pharm. 72, 559 (2015).

J. D. Smart, Adv. Drug Delivery Rev. 57, 1556 (2005).CrossRef

F. Cui, F. Qian, and C. Yin, Int. J. Pharm. 316, 154 (2006).CrossRefPubMed

L. Serra, J. Domenech, and N. A. Peppas, Eur. J. Pharm. Biopharm. 63, 11 (2006).CrossRefPubMed

N. A. Plate, L. I. Valuev, and V. A. Knyazhev, Vestn. Ross. Akad. Nauk 71, 899 (2001).

I. L. Valuev, L. I. Valuev, G. A. Sytov, and N. A. Plate, Biokhimiya 61, 1584 (1996).

10.

M. K. Khoshkbarchi and J. H. Vera, Ind. Eng. Chem. Res. 36, 2445 (1997).CrossRef

11.

K. V. Shevchenko, I. Yu. Nagaev, L. Yu. Alfeeva, L. A. Andreeva, A. A. Kamenskii, N. G. Levitskaya, V. P. Shevchenko, I. A. Grivennikov, and N. F. Myasoedov, Russ. J. Bioorg. Chem. 32, 57 (2006).CrossRef

12.

J. D. Smart, Adv. Drug Delivery Rev. 57, 1612 (2005).CrossRef

13.

D. Banik, S. Kundu, P. Banerjee, R. Dutta, and N. Sarkar, J. Phys. Chem. B 121, 1533 (2017).CrossRefPubMed

Title: Mucoadhesive Polymer Carriers of Intranasal Medicines
Authors: I. L. Valuev
M. Yu. Gorshkova
L. V. Vanchugova
L. I. Valuev
Publication date: 01-05-2019
Publisher: Pleiades Publishing
Published in: Polymer Science, Series A / Issue 3/2019
Print ISSN: 0965-545X
Electronic ISSN: 1555-6107
DOI: https://doi.org/10.1134/S0965545X19020135

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