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2017 | OriginalPaper | Chapter

2. Multifunctional Nanoparticles

Author : Devasena T

Published in: Therapeutic and Diagnostic Nanomaterials

Publisher: Springer Singapore

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Abstract

The functionalization of nanoparticles with one or more specific chemical moieties, so-called ligands, results in multifunctional nanoparticles. They are widely used in biomedical applications, especially drug delivery, cancer therapy, diagnostics, tissue engineering, and molecular biology.

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Attarwala H (2010) Role of antibodies in cancer targeting. J Nat Sci Biol Med 1:53–56. doi:10.4103/0976-9668.71675 CrossRef

Budzynska R, Nevozhay D, Kanska U, Jagiello M, Opolski A, Wietrzyk J, Boratynski J (2007) Antitumor activity of mannanmethotrexate conjugate in vitro and in vivo. Oncol Res 16:415–421. doi:10.3727/000000007783980837

Devi RA, Francis AP, Devasena T (2014) Green-synthesized gold nanocubes functionalized with bisdemethoxycurcumin analog as an ideal anticancer candidate. Green Proc Synth 3(1):47–61. doi:10.1515/gps-2013-0090

Guo S, Huang L (2011) Nanoparticles escaping RES and endosome: challenges for siRNA delivery for cancer therapy. J Nanomater Article ID 742895:12. doi:http://dx.doi.org/10.1155/2011/742895

Gupta A, Gupta RK, Gupta GS (2009) Targeting cells for drug and gene delivery: emerging applications of mannans and mannan binding lectins. J Sci Indus Res 68:465–483

Hanenberg M, Mcafoose J, Kulic L, Welt T, Wirth F, Parizek P (2014) Amyloid- peptide-specific DARPins as a novel class of potential therapeutics for alzheimer disease. J Biol Chem 289:27080–27089. doi:10.1074/jbc.M114.564013) CrossRef

Hilgenbrink AR, Low PS (2005) Folate receptor-mediated drug targeting: from therapeutics to diagnostics. J Pharm Sci 94:2135–2146. doi:10.1002/jps.20457 CrossRef

Jang JY, Lee DY, Park SJ, Byun Y (2003) Immune reactions of lymphocytes and macrophages against PEG-grafted pancreatic islets. Biomaterials 25:3663–3669. doi:10.1016/j.biomaterials.2003.10.062 CrossRef

Kaszuba M, Jones MN (1998) The use of lectins for liposome targeting in drug delivery. Methods Mol Med 9:583–594. doi:10.1385/0-89603-396-1:583

Keefe AD, Pai S, Ellington A (2010) Aptamers as therapeutics. Nat Rev Drug Discov 9:537–550. doi:10.1038/nrd3141 CrossRef

Lungu M, PogonariuA Precup M, Moldovan L, Oancea A, Zarnescu O (1997) Increasing biocompatibility of synthetic polymers for medical use by compounding with collagen. Roum Biotechnol Lett 2:153–161

Muro S (2012) Challenges in design and characterization of ligand-targeted drug delivery systems. J Control Release 164:125–137. doi:10.1016/j.jconrel.2012.05.052 CrossRef

Osseni SA, Lechevallier S, Verelst M, Perriat P, Dexpert-Ghys J, Neumeyer D, Garcia R, Mayer F, Djanashvili K, Peters JA, Magdeleine E, Gros-Dagnac H, Celsis P, Mauricot P (2014) Adolinium oxysulfide nanoparticles as multimodal imaging agents for T ₂-weighted MR, X-ray tomography and photoluminescence. Nanoscale 6:555–564. doi:10.1039/C3NR03982J CrossRef

Otsuka H, Nagasaki Y, Kataoka K (2003) PEGylated nanoparticles for biological and pharmaceutical applications. Adv Drug Deliv Rev 55:403–419. doi:10.1016/S0169-409X(02)00226-0 CrossRef

Schaffner P, Dard MM (2003) Structure and function of RGD peptides involved in bone biology. Cell Mol Life Sci 60:119–132 (1420-682X/03/010119-14)CrossRef

Sosnovik DE, Nahrendorf M, Weissleder R (2008) Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol 103:122–130. doi:10.1007/s00395-008-0710-7 CrossRef

Sperling RA, Parak WJ (2010) Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles. Phil Trans R Soc A 368:1333–1383. doi:10.1098/rsta.2009.0273 CrossRef

Suganya TR, Devasena T (2015) Green synthesis of silver nanorods and optimization of its therapeutic cum toxic dose. J Nanosci Nanotechnol 15(12):9565–9570CrossRef

Svenson S, Prudhomme PK (2012) Multifunctional nanoparticles for drug delivery applications: imaging, targeting, and delivery. Springer Science and Business Media, New YorkCrossRef

Thevenot P, Hu W, Tang L (2008) Surface chemistry influence implant biocompatibility. Curr Top Med Chem 8:270–280CrossRef

Wandtke T, Woźniak J, Kopiński P (2015) Aptamers in diagnostics and treatment of viral infections. Viruses 7:751–780. doi:10.3390/v7020751 CrossRef

Wu X, Chen J, Wu M, Zhao JX (2015) Aptamers: active targeting ligands for cancer diagnosis and therapy. Theranostics 5:322–344. doi:10.7150/thno.10257 CrossRef

Xu W, Bony BA, Kim CR, Baeck JS, Chang Y, Bae J, Chae KS, Kim TJ, Lee GH (2013) Mixed lanthanide oxide nanoparticles as dual imaging agent in biomedicine. Sci Rep 3:3210. doi:10.1038/srep03210

Zavaleta CL, Phillips WT, Soundararajan A, Goins BA (2007) Use of avidin/biotin-liposome system for enhanced peritoneal drug delivery in an ovarian cancer model. Int J Pharm 337:316–328. doi:10.1016/j.ijpharm.2007.01.010 CrossRef

Title: Multifunctional Nanoparticles
Author: Devasena T
Publisher: Springer Singapore
Book: Therapeutic and Diagnostic Nanomaterials
Print ISBN: 978-981-10-0921-1

Electronic ISBN: 978-981-10-0923-5

Copyright Year: 2017
DOI: https://doi.org/10.1007/978-981-10-0923-5_2