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2018 | OriginalPaper | Chapter

9. Nano-Food Toxicity and Regulations

Authors : Nandita Dasgupta, Shivendu Ranjan

Published in: An Introduction to Food Grade Nanoemulsions

Publisher: Springer Singapore

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Abstract

Food nanotechnology has seen exponential growth in last decade due to its unique physicochemical properties; however, the risk associated with this emerging technology has withdrawn ample attention in the past decade. Developing novel food-product for better efficiency is important but analyzing the short term as well as long term toxic effects is more important and that is why rules, regulations and other controlling measures. Nanotoxicity is majorly contributed to the small size and large surface area of nanomaterials, which allow easy dispersion and invasion of anatomical barriers in human body. Unique physio-chemical properties of nanomaterials make the investigation of their toxic consequences intricate and challenging. Nano-toxicity has various effects on human health and diseases as they can easily enter into the humans via different routes, mainly respiratory, dermal and gastrointestinalroutes.
This review focuses on the nanomaterial-cell interactions leading to toxicological responses. Different mechanisms involved in nanoparticle-mediated toxicity with the main focus on oxidative stress, genotoxic and carcinogenic potential has also been discussed. This review provides a better understanding of the current scenario of the nanotoxicology, disease progression due to nanomaterials, and their use in the food industry and medical therapeutics. Briefly, the required rules, regulations and the need of policy makers has been discussed critically. Here in this review, (i) the toxicity of nano-materials used in foods are discussed in brief; (ii) Safety regulations drafted in context of nano-foods have been discussed; (iii) globally many countries e.g. India do not have any strict regulations to control nano-food products, in this regard, the regulations and recommendations which may fit with nano-foods have been pointed out here. This review will be brief note for the policymakers when the nano-toxicology, nano-regulations will come in lime-light.

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Metadata
Title
Nano-Food Toxicity and Regulations
Authors
Nandita Dasgupta
Shivendu Ranjan
Copyright Year
2018
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-6986-4_9

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