Skip to main content
Top

2013 | OriginalPaper | Chapter

5. Nested Sphere Statistics of Skeletal Models

Authors : Stephen M. Pizer, Sungkyu Jung, Dibyendusekhar Goswami, Jared Vicory, Xiaojie Zhao, Ritwik Chaudhuri, James N. Damon, Stephan Huckemann, J. S. Marron

Published in: Innovations for Shape Analysis

Publisher: Springer Berlin Heidelberg

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

We seek a form of object model that exactly and completely captures the interior of most non-branching anatomic objects and simultaneously is well suited for probabilistic analysis on populations of such objects. We show that certain nearly medial, skeletal models satisfy these requirements. These models are first mathematically defined in continuous three-space, and then discrete representations formed by a tuple of spoke vectors are derived. We describe means of fitting these skeletal models into manual or automatic segmentations of objects in a way stable enough to support statistical analysis, and we sketch means of modifying these fits to provide good correspondences of spoke vectors across a training population of objects. Understanding will be developed that these discrete skeletal models live in an abstract space made of a Cartesian product of a Euclidean space and a collection of spherical spaces. Based on this understanding and the way objects change under various rigid and nonrigid transformations, a method analogous to principal component analysis called composite principal nested spheres will be seen to apply to learning a more efficient collection of modes of object variation about a new and more representative mean object than those provided by other representations and other statistical analysis methods. The methods are illustrated by application to hippocampi.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literature
1.
go back to reference Arsigny, V., Commowick, O., Pennec, X., Ayache, N.: A log-Euclidean framework for statistics on diffeomorphisms. In: Medical Image Computing and Computer-Assisted Intervention, vol. 9, pp. 924–931. Springer, Berlin/Heidelberg (2006) Arsigny, V., Commowick, O., Pennec, X., Ayache, N.: A log-Euclidean framework for statistics on diffeomorphisms. In: Medical Image Computing and Computer-Assisted Intervention, vol. 9, pp. 924–931. Springer, Berlin/Heidelberg (2006)
2.
go back to reference Blum, H.: A transformation for extracting new descriptors of shape. In: Wathen-Dunn, W. (ed.) Models for the Perception of Speech and Visual Form. MIT, Cambridge, MA (1967) Blum, H.: A transformation for extracting new descriptors of shape. In: Wathen-Dunn, W. (ed.) Models for the Perception of Speech and Visual Form. MIT, Cambridge, MA (1967)
3.
go back to reference Cates, J., Fletcher, P.T., Styner, M.E., Shenton, R.T.W.: Shape modeling and analysis with entropy-based particle systems. Inf. Process. Med. Imaging 20, 333–345 (2007)CrossRef Cates, J., Fletcher, P.T., Styner, M.E., Shenton, R.T.W.: Shape modeling and analysis with entropy-based particle systems. Inf. Process. Med. Imaging 20, 333–345 (2007)CrossRef
4.
go back to reference Cootes, T.F., Taylor, C., Cooper, D., Graham, J.: Training models of shape from sets of examples. In: Hogg, D., Boyle, R. (eds.) Proceedings of British Machine Vision Conference, pp. 9–18. Springer, Berlin (1992) Cootes, T.F., Taylor, C., Cooper, D., Graham, J.: Training models of shape from sets of examples. In: Hogg, D., Boyle, R. (eds.) Proceedings of British Machine Vision Conference, pp. 9–18. Springer, Berlin (1992)
5.
go back to reference Cootes, T.F., Twining, C.J., Petrović, V.S., Babalola, K.O., Taylor, C.J.: Computing accurate correspondences across groups of images. IEEE Trans. Pattern Anal. Mach. Intell. 32, 1994–2005 (2010)CrossRef Cootes, T.F., Twining, C.J., Petrović, V.S., Babalola, K.O., Taylor, C.J.: Computing accurate correspondences across groups of images. IEEE Trans. Pattern Anal. Mach. Intell. 32, 1994–2005 (2010)CrossRef
6.
go back to reference Damon, J.: Smoothness and geometry of boundaries associated to skeletal structures I: sufficient conditions for smoothness. Ann. Inst. Fourier 53, 1001–1045 (2003)MathSciNetCrossRef Damon, J.: Smoothness and geometry of boundaries associated to skeletal structures I: sufficient conditions for smoothness. Ann. Inst. Fourier 53, 1001–1045 (2003)MathSciNetCrossRef
7.
go back to reference Damon, J.: Swept regions and surfaces: modeling and volumetric properties. Conf. Computational Alg. Geom. 2006, in honor of Andre Galligo. Spl. Issue Theor. Comp. Sci. 392, 66–91 (2008) Damon, J.: Swept regions and surfaces: modeling and volumetric properties. Conf. Computational Alg. Geom. 2006, in honor of Andre Galligo. Spl. Issue Theor. Comp. Sci. 392, 66–91 (2008)
8.
go back to reference Dryden, I.L., Mardia, K.V.: Statistical Shape Analysis. Wiley, Chichester (1998)MATH Dryden, I.L., Mardia, K.V.: Statistical Shape Analysis. Wiley, Chichester (1998)MATH
9.
go back to reference Fletcher, P.T., Lu, C., Pizer, S.M., Joshi, S.: Principal geodesic analysis for the study of nonlinear statistics of shape. IEEE Trans. Med. Imaging 23, 995–1005 (2004)CrossRef Fletcher, P.T., Lu, C., Pizer, S.M., Joshi, S.: Principal geodesic analysis for the study of nonlinear statistics of shape. IEEE Trans. Med. Imaging 23, 995–1005 (2004)CrossRef
10.
go back to reference Fletcher, P.T., Venkatasubramanian, S., Joshi, S.: The geometric median on Riemmanian manifolds with application to robust atlas estimation. NeuroImage 45(1), S143–S152 (2009)CrossRef Fletcher, P.T., Venkatasubramanian, S., Joshi, S.: The geometric median on Riemmanian manifolds with application to robust atlas estimation. NeuroImage 45(1), S143–S152 (2009)CrossRef
11.
go back to reference Han, Q., Pizer, S.M., Damon, J.N.: Interpolation in discrete single figure medial objects. In: Computer Vision and Pattern Recognition (CVPR) – Workshop on Mathematical Methods in Biomedical Image Analysis (MMBIA). IEEE Press (2006) Han, Q., Pizer, S.M., Damon, J.N.: Interpolation in discrete single figure medial objects. In: Computer Vision and Pattern Recognition (CVPR) – Workshop on Mathematical Methods in Biomedical Image Analysis (MMBIA). IEEE Press (2006)
12.
go back to reference Huckemann, S., Ziezold, H.: Principal component analysis for Riemannian manifolds, with an application to triangular shape spaces. Adv. Appl. Probab. 38(2), 299–319 (2006)MathSciNetMATHCrossRef Huckemann, S., Ziezold, H.: Principal component analysis for Riemannian manifolds, with an application to triangular shape spaces. Adv. Appl. Probab. 38(2), 299–319 (2006)MathSciNetMATHCrossRef
13.
go back to reference Huckemann, S., Hotz, T., Munk, A.: Intrinsic shape analysis: geodesic PCA for Riemannian manifolds modulo isometric lie group actions. Stat. Sin. 20(1), 1–58 (2010)MathSciNetMATH Huckemann, S., Hotz, T., Munk, A.: Intrinsic shape analysis: geodesic PCA for Riemannian manifolds modulo isometric lie group actions. Stat. Sin. 20(1), 1–58 (2010)MathSciNetMATH
14.
go back to reference Jung, S., Liu, X., Marron, J.S., Pizer, S.M.: Generalized PCA via the backward stepwise approach in image analysis. In: Angeles, J. (ed.) Brain, Body and Machine: Proceedings of an International Symposium on the 25th Anniversary of McGill University Centre for Intelligent Machines. Advances in Intelligent and Soft Computing, vol. 83, pp. 111–123. Springer, Berlin/Heidelberg (2010) Jung, S., Liu, X., Marron, J.S., Pizer, S.M.: Generalized PCA via the backward stepwise approach in image analysis. In: Angeles, J. (ed.) Brain, Body and Machine: Proceedings of an International Symposium on the 25th Anniversary of McGill University Centre for Intelligent Machines. Advances in Intelligent and Soft Computing, vol. 83, pp. 111–123. Springer, Berlin/Heidelberg (2010)
16.
go back to reference Kendall, D.G., Barden, D., Carne, T.K., Le, H.: Shape and Shape Theory. Wiley, Chichester (1999)MATHCrossRef Kendall, D.G., Barden, D., Carne, T.K., Le, H.: Shape and Shape Theory. Wiley, Chichester (1999)MATHCrossRef
17.
go back to reference Kurtek, S., Ding, Z., Klassen, E., Srivastava, A.: Parameterization-invariant shape statistics and probabilistic classification of anatomical surfaces. Inf. Process. Med. Imaging 22, 147–158 (2011)CrossRef Kurtek, S., Ding, Z., Klassen, E., Srivastava, A.: Parameterization-invariant shape statistics and probabilistic classification of anatomical surfaces. Inf. Process. Med. Imaging 22, 147–158 (2011)CrossRef
18.
go back to reference Leventon, M., Faugeras, O., Grimson, E., Kikinis, R., Wells, W.: Knowledge-based segmentation of medical images. In: Osher, S., Paragios, N. (eds.) Geometric Level Set Methods in Imaging, Vision, and Graphics. Springer, New York (2003) Leventon, M., Faugeras, O., Grimson, E., Kikinis, R., Wells, W.: Knowledge-based segmentation of medical images. In: Osher, S., Paragios, N. (eds.) Geometric Level Set Methods in Imaging, Vision, and Graphics. Springer, New York (2003)
19.
go back to reference Merck, D., Tracton, G., Saboo, R., Levy, J., Chaney, E., Pizer, S.M., Joshi, S.: Training models of anatomic shape variability. Med. Phys. 35, 3584–3596 (2008)CrossRef Merck, D., Tracton, G., Saboo, R., Levy, J., Chaney, E., Pizer, S.M., Joshi, S.: Training models of anatomic shape variability. Med. Phys. 35, 3584–3596 (2008)CrossRef
20.
go back to reference Oguz, I., Cates, J., Fletcher, T., Whitaker, R., Cool, D., Aylward, S., Styner, M.: Entropy-based particle systems and local features for cortical correspondence optimization. In: Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1637–1641. IEEE Press (2008) Oguz, I., Cates, J., Fletcher, T., Whitaker, R., Cool, D., Aylward, S., Styner, M.: Entropy-based particle systems and local features for cortical correspondence optimization. In: Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1637–1641. IEEE Press (2008)
21.
go back to reference Pennec, X.: Statistical computing on manifolds: from Riemannian geometry to computational anatomy. Emerg. Trends Vis. Comput. 5416, 347–386 (2008)CrossRef Pennec, X.: Statistical computing on manifolds: from Riemannian geometry to computational anatomy. Emerg. Trends Vis. Comput. 5416, 347–386 (2008)CrossRef
23.
go back to reference Savadjiev, P., Campbell, J.S.W., Descoteaux, M., Deriche, R., Pike, G., Siddiqi, K.: Labeling of ambiguous sub-voxel fibre bundle configurations in high angular resolution diffusion MRI. NeuroImage 41(1), 58–68 (2008)CrossRef Savadjiev, P., Campbell, J.S.W., Descoteaux, M., Deriche, R., Pike, G., Siddiqi, K.: Labeling of ambiguous sub-voxel fibre bundle configurations in high angular resolution diffusion MRI. NeuroImage 41(1), 58–68 (2008)CrossRef
24.
go back to reference Schulz, J., Jung, S., Huckemann, S.: A collection of internal reports submitted to UNC-Göttingen study group on s-rep change under rotational transformations. University of North Carolina at Chapel Hill (2011) Schulz, J., Jung, S., Huckemann, S.: A collection of internal reports submitted to UNC-Göttingen study group on s-rep change under rotational transformations. University of North Carolina at Chapel Hill (2011)
25.
go back to reference Sen, S.K., Foskey, M., Marron, J.S., Styner, M.A.: Support vector machine for data on manifolds: an application to image analysis. In: Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1195–1198. IEEE Press (2008) Sen, S.K., Foskey, M., Marron, J.S., Styner, M.A.: Support vector machine for data on manifolds: an application to image analysis. In: Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1195–1198. IEEE Press (2008)
26.
go back to reference Shi, X., Styner, M., Lieberman, J., Ibrahim, J.G., Lin, W., Zhu, H.: Intrinsic regression models for manifold-valued data. In: Medical Image Computing and Computer-Assisted Intervention, vol. 5762, pp. 192–199. Springer, Berlin/Heidelberg (2009) Shi, X., Styner, M., Lieberman, J., Ibrahim, J.G., Lin, W., Zhu, H.: Intrinsic regression models for manifold-valued data. In: Medical Image Computing and Computer-Assisted Intervention, vol. 5762, pp. 192–199. Springer, Berlin/Heidelberg (2009)
27.
go back to reference Siddiqi, K., Pizer, S.: Medial Representations: Mathematics, Algorithms and Applications. Springer, Dordrecht (2008)MATHCrossRef Siddiqi, K., Pizer, S.: Medial Representations: Mathematics, Algorithms and Applications. Springer, Dordrecht (2008)MATHCrossRef
28.
go back to reference Sorensen, P., Lo, J., Petersen, A., Dirksen, A., de Bruijne, M.: Dissimilarity-based classification of anatomical tree structures. Inf. Process. Med. Imaging 22, 475–485 (2011)CrossRef Sorensen, P., Lo, J., Petersen, A., Dirksen, A., de Bruijne, M.: Dissimilarity-based classification of anatomical tree structures. Inf. Process. Med. Imaging 22, 475–485 (2011)CrossRef
29.
go back to reference Terriberry, T., Joshi, S., Gerig, G.: Hypothesis testing with nonlinear shape models. Inf. Process. Med. Imaging 19, 15–26 (2005)CrossRef Terriberry, T., Joshi, S., Gerig, G.: Hypothesis testing with nonlinear shape models. Inf. Process. Med. Imaging 19, 15–26 (2005)CrossRef
31.
go back to reference Yang, J., Staib, L., Duncan, J.: Neighbor-constrained segmentation with 3D deformable models. Inf. Process. Med. Imaging 18, 198–209 (2003)CrossRef Yang, J., Staib, L., Duncan, J.: Neighbor-constrained segmentation with 3D deformable models. Inf. Process. Med. Imaging 18, 198–209 (2003)CrossRef
Metadata
Title
Nested Sphere Statistics of Skeletal Models
Authors
Stephen M. Pizer
Sungkyu Jung
Dibyendusekhar Goswami
Jared Vicory
Xiaojie Zhao
Ritwik Chaudhuri
James N. Damon
Stephan Huckemann
J. S. Marron
Copyright Year
2013
Publisher
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-34141-0_5

Premium Partner