2015 | OriginalPaper | Chapter
Preparation of HA-Mineralized CS/PLA Composites Nanofiber GBR Mats
Authors : Yu-Ru Lee, Shu-Juan Fu, Chi-Chang Lin
Published in: 1st Global Conference on Biomedical Engineering & 9th Asian-Pacific Conference on Medical and Biological Engineering
Publisher: Springer International Publishing
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In this work, a composited guided bone regeneration (GBR) membrane made of hydroxyapatite (HA) mineralized on electrospun chitosan (CS)-coated poly (lactic acid) (PLA) nanofiber mat was prepared and compared in terms of mineralization characteristics. Fabrication parameters of CS-co-PLA nanofibers and mineralized of calcium phosphate crystals were discussed in details. Fourier transform infrared spectroscopy (FTIR) showed a compositions of CS/PLA mixture and X-ray diffraction results further indicated that the composition of the deposited mineral was a mixture of dicalcium phosphate dehydrates and apatite. These results indicated the HA crystals can be simple mineralized on CS/PLA nanofiber mat which provides notonly better geometric properties but also biological functions for GBR application.