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Environmental Earth Sciences

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01-05-2015 | Thematic Issue

Removal and recovery of amantadine from water by liquid–liquid extraction

Authors: Yonghui Song, Jian Wei, Yinchen Ma, Ping Zeng, Minghao Kong

Published in: Environmental Earth Sciences | Issue 9/2015

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Abstract

Liquid–liquid extraction (LLE) was firstly introduced for the removal and recovery of amantadine from its aqueous solution. The effects of process conditions, including different types of extractants and diluents, oil to water phase ratio (O/A ratio), initial concentration of amantadine and pH, on the extraction efficiency were investigated. The results showed that when the initial concentration is 1000 mg/L, more than 99.5 % of amantadine can be removed using the mixture of P₂₀₄ and n-octanol (volumetric ratio of 3:2) as mixed extractant, with the initial pH in the range of 8.0–10.0 and O/A ratio of 1:1. The removal efficiency can still be as high as 97.0 % even concentrated amantadine solution (10 g/L) was treated. A mechanism of cation-exchange reaction between amantadine and P₂₀₄ was proposed. Back extraction of amantadine using 2.0 M HCl solution as stripping agent demonstrated that about 51.1 % of amantadine was stripped from the loaded extractant. Present findings suggest that LLE could be a promising technology for the removal and recovery of amantadine from water.

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Title: Removal and recovery of amantadine from water by liquid–liquid extraction
Authors: Yonghui Song
Jian Wei
Yinchen Ma
Ping Zeng
Minghao Kong
Publication date: 01-05-2015
Publisher: Springer Berlin Heidelberg
Published in: Environmental Earth Sciences / Issue 9/2015
Print ISSN: 1866-6280
Electronic ISSN: 1866-6299
DOI: https://doi.org/10.1007/s12665-015-4302-1

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